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Synovial Sarcoma, X Breakpoint 2B (SSX2B) (N-Term) 抗体

SSX2B 适用: 人, 犬, 小鼠, Pig WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2784591
发货至: 中国
  • 抗原 See all Synovial Sarcoma, X Breakpoint 2B (SSX2B) 抗体
    Synovial Sarcoma, X Breakpoint 2B (SSX2B)
    抗原表位
    • 1
    • 1
    • 1
    N-Term
    适用
    人, 犬, 小鼠, Pig
    宿主
    • 3
    克隆类型
    • 3
    多克隆
    标记
    • 3
    非结合性
    应用范围
    • 3
    • 1
    • 1
    Western Blotting (WB)
    序列
    IQKAFDDIAK YFSKEEWEKM KASEKIFYVY MKRKYEAMTK LGFKATLPPF
    预测反应
    Dog: 75%, Human: 100%, Mouse: 82%, Pig: 85%
    产品特性
    This is a rabbit polyclonal antibody against SSX2B. It was validated on Western Blot.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the N-terminal region of Human SSX2B
    Top Product
    Discover our top product SSX2B Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeat freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    Synovial Sarcoma, X Breakpoint 2B (SSX2B)
    别名
    SSX2B (SSX2B 产品)
    背景
    The product of this gene belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneous humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. This gene, and also the SSX1 and SSX4 family members, have been involved in t(X,18)(p11.2,q11.2) translocations that are characteristically found in all synovial sarcomas. This translocation results in the fusion of the synovial sarcoma translocation gene on chromosome 18 to one of the SSX genes on chromosome X. The encoded hybrid proteins are likely responsible for transforming activity. Alternative splicing of this gene results in multiple transcript variants. This gene also has an identical duplicate, GeneID: 6757, located about 45 kb upstream in the opposite orientation on chromosome X.
    Protein Size: 223
    分子量
    24 kDa
    基因ID
    727837
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