PPIA 抗体 (Middle Region)
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- 抗原 See all PPIA 抗体
- PPIA (Peptidylprolyl Isomerase A (Cyclophilin A) (PPIA))
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抗原表位
- Middle Region
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适用
- 人, 小鼠, 大鼠, Cow, 犬, 山羊, 马, 豚鼠, 兔, 绵羊
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PPIA antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 序列
- TAKTEWLDGK HVVFGKVKEG MNIVEAMERF GSRNGKTSKK ITIADCGQLE
- 预测反应
- Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 86%, Rat: 100%, Sheep: 100%
- 产品特性
- This is a rabbit polyclonal antibody against PPIA. It was validated on Western Blot and immunohistochemistry.
- 纯化方法
- Protein A purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human PPIA
- Top Product
- Discover our top product PPIA Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 165 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- PPIA (Peptidylprolyl Isomerase A (Cyclophilin A) (PPIA))
- 别名
- PPIA (PPIA 产品)
- 背景
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PPIA is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. PPIA is a cyclosporin binding-protein and may play a role in cyclosporin A-mediated immunosuppression. The protein can also interact with several HIV proteins, including p55 gag, Vpr, and capsid protein, and has been shown to be necessary for the formation of infectious HIV virions.The protein encoded by this gene is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. This protein is a cyclosporin binding-protein. It may play a role in cyclosporin A-mediated immunosuppression. This protein can interact with several HIV proteins including p55 gag, Vpr, and capsid protein. It has been shown to be necessary for the formation of infectious HIV virions. Multiple pseudogenes that map to different chromosomes have been reported. Three alternatively spliced transcript variants encoding two distinct isoforms have been observed.
Alias Symbols: CYPA, CYPH, MGC117158, MGC12404, MGC23397
Protein Interaction Partner: LNX1, HUWE1, UBC, TCF4, FUS, gag, MDM2, RPL23A, SRPK2, SRPK1, ESR1, UBD, TERT, RAD52, VCAM1, ITGA4, FN1, HCVgp1, LIG4, PAXIP1, RB1, APP, CPLX1, SNX3, TAGLN2, SOD1, RPA2, RAD23B, PTMA, IGBP1, ENO1, AKT1, USP4, CDK2, COPS5, CUL1, CUL3, CUL4B, NEDD8, CD99, C
Protein Size: 165 - 分子量
- 18 kDa
- 基因ID
- 5478
- NCBI登录号
- NM_021130, NP_066953
- UniProt
- P62937
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