This gene encodes a member of the AT-rich interaction domain (ARID) family of DNA binding proteins. The encoded protein forms a histone H3K9Me2 demethylase complex with PHD finger protein 2 and regulates the transcription of target genes involved in adipogenesis and liver development. This gene also plays a role in cell growth and differentiation of B-lymphocyte progenitors, and single nucleotide polymorphisms in this gene are associated with acute lymphoblastic leukemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Alias Symbols: DESRT, MRF-2, MRF2 Protein Interaction Partner: UBC, SOX2, HDAC2, HDAC1, SUMO1, CAND1, ISG15, ELAVL1, SUMO2, Protein Size: 318