MED25 抗体 (N-Term)
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- 抗原 See all MED25 抗体
- MED25 (Mediator Complex Subunit 25 (MED25))
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠, Cow, 犬, Pig, 豚鼠, 斑马鱼
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This MED25 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Chromatin Immunoprecipitation (ChIP)
- 序列
- EGLRKHYLLP AIEYFNGGPP AETDFGGDYG GTQYSLVVFN TVDCAPESYV
- 预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 85%, Human: 100%, Mouse: 100%, Pig: 100%, Rat: 100%, Zebrafish: 100%
- 产品特性
- This is a rabbit polyclonal antibody against MED25. It was validated on Western Blot.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human MED25
- Top Product
- Discover our top product MED25 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 747 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Role for human mediator subunit MED25 in recruitment of mediator to promoters by endoplasmic reticulum stress-responsive transcription factor ATF6?." in: The Journal of biological chemistry, Vol. 288, Issue 36, pp. 26179-87, (2013) (PubMed).
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Role for human mediator subunit MED25 in recruitment of mediator to promoters by endoplasmic reticulum stress-responsive transcription factor ATF6?." in: The Journal of biological chemistry, Vol. 288, Issue 36, pp. 26179-87, (2013) (PubMed).
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- 抗原
- MED25 (Mediator Complex Subunit 25 (MED25))
- 别名
- MED25 (MED25 产品)
- 别名
- Arc92 antibody, CG12254 antibody, Dmel\\CG12254 antibody, LD07688 antibody, Med25 antibody, dARC92 antibody, dDrip97 antibody, med25 antibody, ACID1 antibody, ARC92 antibody, CMT2B2 antibody, P78 antibody, PTOV2 antibody, RGD1305137 antibody, 2610034E13Rik antibody, 2610529E18Rik antibody, ESTM2 antibody, X83308 antibody, zgc:63555 antibody, Mediator complex subunit 25 antibody, mediator complex subunit 25 antibody, mediator complex subunit 25 S homeolog antibody, MED25 antibody, med25 antibody, Med25 antibody, med25.S antibody
- 背景
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This gene encodes a component of the transcriptional coactivator complex termed the Mediator complex. This complex is required for transcription of most RNA polymerase II-dependent genes. The encoded protein plays a role in chromatin modification and in preinitiation complex assembly. Mutations in this gene are associated with Charcot-Marie-Tooth disease type 2B2.
Alias Symbols: ACID1, ARC92, CMT2B2, DKFZp434K0512, MGC70671, P78, PTOV2, TCBAP0758
Protein Interaction Partner: UBC, MED19, MED26, EPAS1, NOTCH1, DREB2A, CTDP1, MED6, THRA, RXRA, RARA, MED1, NR3C1, ESR1, CREBBP, SREBF1, MED25, MED15, MED16, MED13, MED12, MED7, MED17, MED23, MED14, CDK8, ZC3H13, QKI, TRIP4, TADA2A, MED28, OBFC1, TRRAP, UL48, MED9, MED8, HCFC1, MED10
Protein Size: 747 - 分子量
- 78 kDa
- 基因ID
- 81857
- NCBI登录号
- NM_030973, NP_112235
- UniProt
- Q71SY5
- 途径
- Nuclear Hormone Receptor Binding, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha, Production of Molecular Mediator of Immune Response
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