FLASH 抗体 (N-Term)
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- 抗原 See all FLASH (CASP8AP2) 抗体
- FLASH (CASP8AP2) (CASP8 Associated Protein 2 (CASP8AP2))
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抗原表位
- N-Term
- 适用
- 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, Pig, 兔
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This FLASH antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- SLKKNISALI KTARVEINRK DEEISNLHQR LSEFPHFRNN HKTARTFDTV
- 预测反应
- Cow: 93%, Dog: 86%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 93%, Rabbit: 93%, Rat: 100%
- 产品特性
- This is a rabbit polyclonal antibody against CASP8AP2. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human CASP8AP2
- Top Product
- Discover our top product CASP8AP2 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 1982 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Buffer optimization for high resolution of human lung cancer tissue proteins by two-dimensional gel electrophoresis." in: Biotechnology letters, Vol. 31, Issue 1, pp. 31-7, (2008) (PubMed).
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Buffer optimization for high resolution of human lung cancer tissue proteins by two-dimensional gel electrophoresis." in: Biotechnology letters, Vol. 31, Issue 1, pp. 31-7, (2008) (PubMed).
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- 抗原
- FLASH (CASP8AP2) (CASP8 Associated Protein 2 (CASP8AP2))
- 别名
- CASP8AP2 (CASP8AP2 产品)
- 别名
- CASP8AP2 antibody, FLASH antibody, fc74h10 antibody, wu:fc74h10 antibody, zgc:113449 antibody, CED-4 antibody, RIP25 antibody, AA387232 antibody, D4Ertd659e antibody, mKIAA1315 antibody, caspase 8 associated protein 2 antibody, CASP8AP2 antibody, casp8ap2 antibody, Casp8ap2 antibody
- 背景
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CASP8AP2 is highly similar to FLASH, a mouse apoptotic protein identified by its interaction with the death-effector domain (DED) of caspase 8. Studies of FLASH protein suggested that this protein may be a component of the death-inducing signaling complex that includes Fas receptor, Fas-binding adapter FADD, and caspase 8, and plays a regulatory role in Fas-mediated apoptosis.This protein is highly similar to FLASH, a mouse apoptotic protein identified by its interaction with the death-effector domain (DED) of caspase 8. Studies of FLASH protein suggested that this protein may be a component of the death-inducing signaling complex that includes Fas receptor, Fas-binding adapter FADD, and caspase 8, and plays a regulatory role in Fas-mediated apoptosis. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: CED-4, FLASH, FLJ11208, KIAA1315, RIP25
Protein Interaction Partner: ced-3, BCL2L1, PML, CTBP2, CREM, SUMO1, SUMO2, PIAS1, CASP10, TRIM21, UBC, CALM1, UBE2I, SREBF2, GLUL, SP100, CASP8AP2, FADD, TRAF2, CASP8, FAS,
Protein Size: 1982 - 分子量
- 223 kDa
- 基因ID
- 9994
- NCBI登录号
- NM_012115, NP_036247
- UniProt
- Q9UKL3
- 途径
- Chromatin Binding, Positive Regulation of Endopeptidase Activity
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