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FLASH 抗体 (N-Term)

CASP8AP2 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, Pig, 兔 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2784233
发货至: 中国
  • 抗原 See all FLASH (CASP8AP2) 抗体
    FLASH (CASP8AP2) (CASP8 Associated Protein 2 (CASP8AP2))
    抗原表位
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, Pig, 兔
    宿主
    • 20
    克隆类型
    • 20
    多克隆
    标记
    • 13
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This FLASH antibody is un-conjugated
    应用范围
    • 13
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    序列
    SLKKNISALI KTARVEINRK DEEISNLHQR LSEFPHFRNN HKTARTFDTV
    预测反应
    Cow: 93%, Dog: 86%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 93%, Rabbit: 93%, Rat: 100%
    产品特性
    This is a rabbit polyclonal antibody against CASP8AP2. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the N terminal region of human CASP8AP2
    Top Product
    Discover our top product CASP8AP2 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 1982 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Lee, Pi, Lee: "Buffer optimization for high resolution of human lung cancer tissue proteins by two-dimensional gel electrophoresis." in: Biotechnology letters, Vol. 31, Issue 1, pp. 31-7, (2008) (PubMed).

  • 抗原
    FLASH (CASP8AP2) (CASP8 Associated Protein 2 (CASP8AP2))
    别名
    CASP8AP2 (CASP8AP2 产品)
    别名
    CASP8AP2 antibody, FLASH antibody, fc74h10 antibody, wu:fc74h10 antibody, zgc:113449 antibody, CED-4 antibody, RIP25 antibody, AA387232 antibody, D4Ertd659e antibody, mKIAA1315 antibody, caspase 8 associated protein 2 antibody, CASP8AP2 antibody, casp8ap2 antibody, Casp8ap2 antibody
    背景
    CASP8AP2 is highly similar to FLASH, a mouse apoptotic protein identified by its interaction with the death-effector domain (DED) of caspase 8. Studies of FLASH protein suggested that this protein may be a component of the death-inducing signaling complex that includes Fas receptor, Fas-binding adapter FADD, and caspase 8, and plays a regulatory role in Fas-mediated apoptosis.This protein is highly similar to FLASH, a mouse apoptotic protein identified by its interaction with the death-effector domain (DED) of caspase 8. Studies of FLASH protein suggested that this protein may be a component of the death-inducing signaling complex that includes Fas receptor, Fas-binding adapter FADD, and caspase 8, and plays a regulatory role in Fas-mediated apoptosis. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: CED-4, FLASH, FLJ11208, KIAA1315, RIP25
    Protein Interaction Partner: ced-3, BCL2L1, PML, CTBP2, CREM, SUMO1, SUMO2, PIAS1, CASP10, TRIM21, UBC, CALM1, UBE2I, SREBF2, GLUL, SP100, CASP8AP2, FADD, TRAF2, CASP8, FAS,
    Protein Size: 1982
    分子量
    223 kDa
    基因ID
    9994
    NCBI登录号
    NM_012115, NP_036247
    UniProt
    Q9UKL3
    途径
    Chromatin Binding, Positive Regulation of Endopeptidase Activity
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