NUMA1 抗体 (C-Term)
(1 reference)-
- 抗原 See all NUMA1 抗体
- NUMA1 (Nuclear Mitotic Apparatus Protein 1 (NUMA1))
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抗原表位
- C-Term
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适用
- 人, 小鼠, 大鼠, 豚鼠, 马, 犬, Cow, 兔
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This NUMA1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- AQRLQAQLNE LQAQLSQKEQ AAEHYKLQME KAKTHYDAKK QQNQELQEQL
- 预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
- 产品特性
- This is a rabbit polyclonal antibody against NUMA1. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human NUMA1
- Top Product
- Discover our top product NUMA1 Primary Antibody
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anti-Nuclear Mitotic Apparatus Protein 1 (NUMA1) (AA 1-309) antibody
NUMA1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Mitotic Apparatus Protein 1 (NUMA1) (N-Term) antibodyNUMA1 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Mitotic Apparatus Protein 1 (NUMA1) (AA 627-870) antibodyNUMA1 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Mitotic Apparatus Protein 1 (NUMA1) (AA 1-1193) antibodyNUMA1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Mitotic Apparatus Protein 1 (NUMA1) (AA 200-306) antibodyNUMA1 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 1C5 unconjugated
anti-Nuclear Mitotic Apparatus Protein 1 (NUMA1) (AA 1-1193) antibodyNUMA1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Nuclear Mitotic Apparatus Protein 1 (NUMA1) antibodyNUMA1 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-Nuclear Mitotic Apparatus Protein 1 (NUMA1) (N-Term) antibodyNUMA1 适用: 人, 小鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Mitotic Apparatus Protein 1 (NUMA1) (AA 1700-2115) antibodyNUMA1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Mitotic Apparatus Protein 1 (NUMA1) (AA 1700-2115) antibodyNUMA1 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C4 unconjugated
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 2115 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "Comprehensive analysis of NuMA variation in breast cancer." in: BMC cancer, Vol. 8, pp. 71, (2008) (PubMed).
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: "Comprehensive analysis of NuMA variation in breast cancer." in: BMC cancer, Vol. 8, pp. 71, (2008) (PubMed).
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- 抗原
- NUMA1 (Nuclear Mitotic Apparatus Protein 1 (NUMA1))
- 别名
- NUMA1 (NUMA1 产品)
- 背景
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NuMA is a structural element in maintaining nuclear integrity. A critical spindle pole-associated mechanism, called the END (Emi1/NuMA/dynein-dynactin) network, spatially restricts APC/C activity in early mitosis. The entire coding region and exon-intron boundaries of NuMa were screened in 92 familial breast cancer patients. But the results do not support the role of NuMA variants as breast cancer susceptibility alleles.
Alias Symbols: NUMA
Protein Interaction Partner: CCDC57, GMCL1, BRAP, DVL3, DVL2, DVL1, UBC, LGR4, ERG, RPA3, RPA2, RPA1, RNF2, EZH2, BMI1, SUZ12, EED, YWHAQ, LMNA, CBX6, WHSC1, HSP90AB1, HSP90AA1, ESR1, CDK6, VCP, SMURF1, MDC1, TP53BP1, ECT2, NCSTN, DDB1, EMILIN1, DYNLL1, RAE1, NUP98, CDK2, TERF2IP, TE
Protein Size: 2115 - 分子量
- 238 kDa
- 基因ID
- 4926
- NCBI登录号
- NM_006185, NP_006176
- UniProt
- Q14980
- 途径
- Caspase Cascade in Apoptosis, Regulation of Actin Filament Polymerization, M Phase
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