SPRY2 抗体 (N-Term)
-
- 抗原 See all SPRY2 抗体
- SPRY2 (Sprouty Homolog 2 (SPRY2))
-
抗原表位
- N-Term
-
适用
- 人, 小鼠, 大鼠, 犬, Cow, 马, 兔, Pig, 豚鼠
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This SPRY2 antibody is un-conjugated
-
应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 序列
- MEARAQSGNG SQPLLQTPRD GGRQRGEPDP RDALTQQVHV LSLDQIRAIR
- 预测反应
- Cow: 93%, Dog: 100%, Guinea Pig: 92%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 86%, Rat: 100%
- 产品特性
- This is a rabbit polyclonal antibody against SPRY2. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human SPRY2
- Top Product
- Discover our top product SPRY2 Primary Antibody
-
-
- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
-
Antigen size: 315 AA
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
-
Clostridium perfringens Keratitis Leading to Blinding Panophthalmitis." in: Cornea, Vol. 27, Issue 10, pp. 1200-3, (2008) (PubMed).
: "
-
Clostridium perfringens Keratitis Leading to Blinding Panophthalmitis." in: Cornea, Vol. 27, Issue 10, pp. 1200-3, (2008) (PubMed).
-
- 抗原
- SPRY2 (Sprouty Homolog 2 (SPRY2))
- 别名
- SPRY2 (SPRY2 产品)
- 别名
- wu:fk66h11 antibody, wu:fk93e11 antibody, zgc:110440 antibody, hspry2 antibody, xspry2 antibody, sprouty2 antibody, Xsprouty2 antibody, sprouty-2 antibody, Xtsprouty2 antibody, hSPRY2 antibody, sprouty RTK signaling antagonist 2 antibody, sprouty RTK signaling antagonist 2 S homeolog antibody, sprouty homolog 2 (Drosophila) antibody, spry2 antibody, SPRY2 antibody, spry2.S antibody, Spry2 antibody
- 背景
-
SPRY2 is a protein belonging to the sprouty family. It contains a carboxyl-terminal cysteine-rich domain essential for the inhibitory activity on receptor tyrosine kinase signaling proteins and is required for growth factor stimulated translocation of the protein to membrane ruffles. In primary dermal endothelial cells this gene is transiently upregulated in response to fibroblast growth factor two. SPRY2 is indirectly involved in the non-cell autonomous inhibitory effect on fibroblast growth factor two signaling. The protein interacts with Cas-Br-M (murine) ectropic retroviral transforming sequence, and can function as a bimodal regulator of epidermal growth factor receptor/mitogen-activated protein kinase signaling. SPRY2 may play a role in alveoli branching during lung development as shown by a similar mouse protein.This gene encodes a protein belonging to the sprouty family. The encoded protein contains a carboxyl-terminal cysteine-rich domain essential for the inhibitory activity on receptor tyrosine kinase signaling proteins and is required for growth factor stimulated translocation of the protein to membrane ruffles. In primary dermal endothelial cells this gene is transiently upregulated in response to fibroblast growth factor two. This protein is indirectly involved in the non-cell autonomous inhibitory effect on fibroblast growth factor two signaling. The protein interacts with Cas-Br-M (murine) ectropic retroviral transforming sequence, and can function as a bimodal regulator of epidermal growth factor receptor/mitogen-activated protein kinase signaling. This protein may play a role in alveoli branching during lung development as shown by a similar mouse protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: MGC23039, hSPRY2
Protein Interaction Partner: PTGER3, PRKAB2, KRTAP4-11, ATRIP, KRTAP5-6, KRTAP10-3, KRTAP10-8, KRTAP10-5, KRTAP10-11, KRTAP10-1, KRTAP10-9, LCE3E, KRTAP5-9, GP9, OTX1, MLLT6, MEOX2, MDFI, LASP1, LCE2D, LCE1B, RUNX1T1, AQP1, LCE3C, LCE4A, ZNF417, HEXIM2, CATSPER1, LONRF1, KRTAP4-7, KR
Protein Size: 315 - 分子量
- 35 kDa
- 基因ID
- 10253
- NCBI登录号
- NM_005842, NP_005833
- UniProt
- O43597
- 途径
- EGFR Signaling Pathway, Sensory Perception of Sound, EGFR Downregulation
-