ING1 抗体 (C-Term)
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- 抗原 See all ING1 抗体
- ING1 (Inhibitor of Growth Family, Member 1 (ING1))
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抗原表位
- C-Term
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适用
- 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 斑马鱼, 马, 兔
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ING1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- EKKAKTSKKK KRSKAKAERE ASPADLPIDP NEPTYCLCNQ VSYGEMIGCD
- 预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 86%
- 产品特性
- This is a rabbit polyclonal antibody against ING1. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Protein A purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human ING1
- Top Product
- Discover our top product ING1 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 279 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- ING1 (Inhibitor of Growth Family, Member 1 (ING1))
- 别名
- ING1 (ING1 产品)
- 别名
- p24ING1c antibody, p33 antibody, p33ING1 antibody, p33ING1b antibody, p47 antibody, p47ING1a antibody, p33ING1c antibody, zgc:136918 antibody, ING1 antibody, 2610028J21Rik antibody, AA407184 antibody, AI875420 antibody, mING1h antibody, p33Ing1 antibody, p37Ing1b antibody, xing1 antibody, inhibitor of growth family member 1 antibody, inhibitor of growth family, member 1 antibody, inhibitor of growth family member 1 S homeolog antibody, ING1 antibody, Ing1 antibody, ing1 antibody, ing1.S antibody
- 背景
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ING1 is a tumor suppressor protein that can induce cell growth arrest and apoptosis. The protein is a nuclear protein that physically interacts with the tumor suppressor protein TP53 and is a component of the p53 signaling pathway. Reduced expression and rearrangement of ING1 gene have been detected in various cancers.This gene encodes a tumor suppressor protein that can induce cell growth arrest and apoptosis. The encoded protein is a nuclear protein that physically interacts with the tumor suppressor protein TP53 and is a component of the p53 signaling pathway. Reduced expression and rearrangement of this gene have been detected in various cancers. Multiple alternatively spliced transcript variants encoding distinct isoforms have been reported.
Alias Symbols: p24ING1c, p33, p33ING1, p33ING1b, p47, p47ING1a
Protein Interaction Partner: SIRT1, SIRT2, UBC, HDAC1, KIAA0101, PCNA, RBP1, RBBP7, RBBP4, HDAC2, BRMS1L, SIN3A, BRMS1, SAP30, ELAVL1, SMURF1, COPS2, NQO1, HIST2H3C, MRGBP, YWHAZ, YWHAH, YWHAG, YWHAE, YWHAB, KPNA2, KPNB1, YWHAQ, SFN, ESR1, LMNA, CDKN2A, TP53, KAT2B, DMAP1, EP300, HHT
Protein Size: 279 - 分子量
- 32 kDa
- 基因ID
- 3621
- NCBI登录号
- NM_198219, NP_937862
- UniProt
- Q5T9H0
- 途径
- Protein targeting to Nucleus, Autophagy
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