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- 抗原 See all SSX4B 抗体
- SSX4B (Synovial Sarcoma, X Breakpoint 4B (SSX4B))
- 抗原表位
- Middle Region
- 适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SSX4B antibody is un-conjugated
- 应用范围
- Western Blotting (WB)
- 序列
- MRSKRAADFH GNDFGNDRNH RNQVERPQMT FGSLQRIFPK IMPKKPAEEE
- 预测反应
- Human: 100%
- 产品特性
- This is a rabbit polyclonal antibody against SSX4B. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human SSX4B
- Top Product
- Discover our top product SSX4B Primary Antibody
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anti-Synovial Sarcoma, X Breakpoint 4B (SSX4B) (AA 1-188) antibody
SSX4B 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 188 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- SSX4B (Synovial Sarcoma, X Breakpoint 4B (SSX4B))
- 别名
- SSX4B (SSX4B 产品)
- 别名
- CT5.4 antibody, SSX family member 4B antibody, SSX4B antibody
- 背景
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The product of this gene belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneously humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. SSX1, SSX2 and SSX4 genes have been involved in the t(X,18) translocation characteristically found in all synovial sarcomas. This translocation results in the fusion of the synovial sarcoma translocation gene on chromosome 18 to one of the SSX genes on chromosome X. Chromosome Xp11 contains a segmental duplication resulting in two identical copies of synovial sarcoma, X breakpoint 4, SSX4 and SSX4B, in tail-to-tail orientation. This gene, SSX4B, represents the more centromeric copy. Two transcript variants encoding distinct isoforms have been identified for this gene.
Alias Symbols: SSX4, CT5.4
Protein Interaction Partner: HIF1A,
Protein Size: 188 - 分子量
- 22 kDa
- 基因ID
- 548313
- NCBI登录号
- NM_001034832, NP_001030004
- UniProt
- O60224
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