SPOP-B 抗体 (C-Term)
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- 抗原 See all SPOP-B 抗体
- SPOP-B (Speckle-Type POZ Protein (SPOP-B))
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抗原表位
- C-Term
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适用
- 人, 小鼠, 大鼠, 斑马鱼, Cow, 犬, 兔, 豚鼠, 马
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SPOP-B antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- YHASDVLETS GWKSMVVSHP HLVAEAYRSL ASAQCPFLGP PRKRLKQS
- 预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
- 产品特性
- This is a rabbit polyclonal antibody against SPOP. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human SPOP
- Top Product
- Discover our top product SPOP-B Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 374 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- SPOP-B (Speckle-Type POZ Protein (SPOP-B))
- 别名
- SPOP (SPOP-B 产品)
- 别名
- BTBD32 antibody, TEF2 antibody, AI315626 antibody, Pcif1 antibody, zgc:64140 antibody, spop antibody, tef2 antibody, speckle type BTB/POZ protein antibody, speckle-type POZ protein antibody, speckle type POZ protein S homeolog antibody, SPOP antibody, Spop antibody, spop antibody, spop.S antibody
- 背景
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SPOP may modulate the transcriptional repression activities of death-associated protein 6 (DAXX), which interacts with histone deacetylase, core histones, and other histone-associated proteins. In mouse, the protein binds to the putative leucine zipper domain of macroH2A1.2, a variant H2A histone that is enriched on inactivated X chromosomes. The BTB/POZ domain of this protein has been shown in other proteins to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes. This gene encodes a protein that may modulate the transcriptional repression activities of death-associated protein 6 (DAXX), which interacts with histone deacetylase, core histones, and other histone-associated proteins. In mouse, the encoded protein binds to the putative leucine zipper domain of macroH2A1.2, a variant H2A histone that is enriched on inactivated X chromosomes. The BTB/POZ domain of this protein has been shown in other proteins to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes. Alternative splicing of this gene results in multiple transcript variants encoding the same protein.
Alias Symbols: TEF2
Protein Interaction Partner: CUL3, SPOP, DEK, GLI2, AR, ATM, RXRB, MYD88, DAXX, NCOA3, SRRM1, GIT2, FADD, PIAS1, UBC, UBE2E3, PIP4K2B, ESR1, BMI1, RTN3, H2AFY, DPPA2, ZBTB16, HCST, TRAF1, PDX1, DDIT3, TRAF6, SIRT2, DOK2, PIP5K1B, GDI1, KPNA6,
Protein Size: 374 - 分子量
- 42 kDa
- 基因ID
- 8405
- NCBI登录号
- NM_001007226, NP_001007227
- UniProt
- O43791
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