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RFT1 抗体 (N-Term)

RFT1 适用: 人, 犬, 小鼠, Cow, 豚鼠, 马, 兔, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2784093
发货至: 中国
  • 抗原 See all RFT1 抗体
    RFT1 (RFT1 Homolog (RFT1))
    抗原表位
    • 8
    • 8
    • 7
    • 1
    • 1
    N-Term
    适用
    人, 犬, 小鼠, Cow, 豚鼠, 马, 兔, 大鼠
    宿主
    • 17
    • 1
    克隆类型
    • 18
    多克隆
    标记
    • 8
    • 2
    • 2
    • 2
    • 2
    • 2
    This RFT1 antibody is un-conjugated
    应用范围
    • 17
    • 14
    • 13
    • 3
    • 1
    Western Blotting (WB)
    序列
    GTQRDWSQTL NLLWLTVPLG VFWSLFLGWI WLQLLEVPDP NVVPHYATGV
    预测反应
    Cow: 92%, Dog: 100%, Guinea Pig: 92%, Horse: 92%, Human: 100%, Mouse: 85%, Rabbit: 92%, Rat: 92%
    产品特性
    This is a rabbit polyclonal antibody against RFT1. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the N terminal region of human RFT1
    Top Product
    Discover our top product RFT1 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 541 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    RFT1 (RFT1 Homolog (RFT1))
    别名
    RFT1 (RFT1 产品)
    别名
    GB14370 antibody, CDG1N antibody, D930025H04 antibody, RGD1562654 antibody, protein RFT1 homolog antibody, RFT1 homolog antibody, LOC412489 antibody, LOC100453537 antibody, RFT1 antibody, rft1 antibody, LOC100633251 antibody, LOC100651701 antibody, Rft1 antibody
    背景
    N-glycosylation of proteins follows a highly conserved pathway that begins with the synthesis of a!!Man(5)GlcNAc(2)-dolichylpyrophosphate (PP-Dol) intermediate on the cytoplasmic side of the endoplasmic reticulum (ER) membrane followed by the translocation of Man(5)GlcNAc (2)-PP-Dol to the luminal side of the ER membrane. RFT1 is the flippase enzyme that catalyzes this translocation.N-glycosylation of proteins follows a highly conserved pathway that begins with the synthesis of a Man(5)GlcNAc(2)-dolichylpyrophosphate (PP-Dol) intermediate on the cytoplasmic side of the endoplasmic reticulum (ER) membrane followed by the translocation of Man(5)GlcNAc (2)-PP-Dol to the luminal side of the ER membrane. RFT1 is the flippase enzyme that catalyzes this translocation (Helenius et al., 2002 [PubMed 11807558]).[supplied by OMIM].
    Alias Symbols: CDG1N
    Protein Interaction Partner: PSMA3, UBC, NEDD4,
    Protein Size: 541
    分子量
    60 kDa
    基因ID
    91869
    NCBI登录号
    NM_052859, NP_443091
    UniProt
    Q96AA3
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