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DISP1 抗体 (Middle Region)

DISP1 适用: 人, 小鼠, 大鼠, 马, 兔, 斑马鱼, Pig WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2784069
发货至: 中国
  • 抗原 See all DISP1 抗体
    DISP1 (Dispatched Homolog 1 (DISP1))
    抗原表位
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    适用
    人, 小鼠, 大鼠, 马, 兔, 斑马鱼, Pig
    宿主
    • 5
    • 1
    克隆类型
    • 6
    多克隆
    标记
    • 6
    This DISP1 antibody is un-conjugated
    应用范围
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    序列
    FVLCDVWNYT KFDKPHAETS ETVSITLQHA ALSMFVTSFT TAAAFYANYV
    预测反应
    Horse: 93%, Human: 100%, Mouse: 93%, Pig: 86%, Rabbit: 100%, Rat: 86%, Zebrafish: 79%
    产品特性
    This is a rabbit polyclonal antibody against DISP1. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the middle region of human DISP1
    Top Product
    Discover our top product DISP1 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 1524 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    DISP1 (Dispatched Homolog 1 (DISP1))
    别名
    DISP1 (DISP1 产品)
    别名
    DISP1 antibody, DISPA antibody, 1190008H24Rik antibody, DispA antibody, con antibody, zgc:111866 antibody, dispatched antibody, dispatched RND transporter family member 1 antibody, dispatched homolog 1 (Drosophila) antibody, CpipJ_CPIJ008642 antibody, DISP1 antibody, Disp1 antibody, disp1 antibody
    背景
    DISP1 functions in hedgehog (Hh) signaling. Regulates the release and extracellular accumulation of cholesterol-modified hedgehog proteins and is hence required for effective production of the Hh signal.The pattern of cellular proliferation and differentiation that leads to normal development of embryonic structures often depends upon the localized production of secreted protein signals. Cells surrounding the source of a particular signal respond in a graded manner according to the effective concentration of the signal, and this response produces the pattern of cell types constituting the mature structure. A novel segment-polarity gene known as dispatched has been identified in Drosophila and its protein product is required for normal Hedgehog (Hh) signaling. This gene is one of two human homologs of Drosophila dispatched and, based on sequence identity to its mouse counterpart, the encoded protein may play an essential role in Hh patterning activities in the early embryo.
    Alias Symbols: DISPA, DKFZP434I0428, FLJ43740, MGC104180, MGC13130, MGC16796
    Protein Interaction Partner: LAPTM5, UBC,
    Protein Size: 1524
    分子量
    171 kDa
    基因ID
    84976
    NCBI登录号
    NM_032890, NP_116279
    UniProt
    Q96F81
    途径
    Hedgehog Signaling
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