ORAI1 抗体 (N-Term)
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- 抗原 See all ORAI1 抗体
- ORAI1 (ORAI Calcium Release-Activated Calcium Modulator 1 (ORAI1))
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抗原表位
- N-Term
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适用
- 人, 小鼠, 马
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ORAI1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- HPEPAPPPSR SSPELPPSGG STTSGSRRSR RRSGDGEPPG APPPPPSAVT
- 预测反应
- Horse: 83%, Human: 100%, Mouse: 79%
- 产品特性
- This is a rabbit polyclonal antibody against ORAI1. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human ORAI1
- Top Product
- Discover our top product ORAI1 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 301 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- ORAI1 (ORAI Calcium Release-Activated Calcium Modulator 1 (ORAI1))
- 别名
- ORAI1 (ORAI1 产品)
- 别名
- CRACM1 antibody, ORAT1 antibody, TMEM142A antibody, RGD1311873 antibody, D730049H07Rik antibody, Tmem142a antibody, orai-1 antibody, im:7146264 antibody, orai1 antibody, tmem142a antibody, zgc:109721 antibody, orai2 antibody, ORAI1 antibody, LOC100218031 antibody, ORAI calcium release-activated calcium modulator 1 antibody, ORAI calcium release-activated calcium modulator 1b antibody, ORAI calcium release-activated calcium modulator 1 S homeolog antibody, ORAI1 antibody, Orai1 antibody, orai1b antibody, orai1.S antibody, orai1 antibody
- 背景
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ORAI1 belongs to the Orai family. ORAI1 (CRACM1) is a plasma membrane protein essential for store-operated calcium entry. Defects in ORAI1 are a cause of severe combined immunodeficiency with CRAC channel dysfunction (CRAC-SCID).CRACM1 is a plasma membrane protein essential for store-operated calcium entry (Vig et al., 2006 [PubMed 16645049]).[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-331 BC075831.1 1-331 332-844 BC013386.1 220-732 845-990 BC075831.1 845-990 991-1490 BG574128.1 52-551 1491-1496 AK027372.1 1235-1240
Alias Symbols: CRACM1, FLJ14466, TMEM142A, ORAT1
Protein Interaction Partner: UBQLN1, UBC, TRPC3, TRPC6,
Protein Size: 301 - 分子量
- 33 kDa
- 基因ID
- 84876
- NCBI登录号
- NM_032790, NP_116179
- UniProt
- Q96D31
- 途径
- TCR Signaling, BCR Signaling
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