Protocadherin gamma Subfamily A, 4 (PCDHGA4) (N-Term) 抗体
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- 抗原 See all Protocadherin gamma Subfamily A, 4 (PCDHGA4) 抗体
- Protocadherin gamma Subfamily A, 4 (PCDHGA4)
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抗原表位
- N-Term
- 适用
- 人, 小鼠, 大鼠, 斑马鱼, Cow, 犬, 豚鼠, 马
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- 非结合性
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应用范围
- Western Blotting (WB)
- 序列
- GDPVRSGTAR ILIILVDTND NAPVFTQPEY HVSVRENVPV GTRLLTVKAT
- 预测反应
- Cow: 86%, Dog: 93%, Guinea Pig: 93%, Horse: 86%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 86%
- 产品特性
- This is a rabbit polyclonal antibody against PCDHGA4. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human PCDHGA4
- Top Product
- Discover our top product PCDHGA4 Primary Antibody
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anti-Protocadherin gamma Subfamily A, 4 (PCDHGA4) (AA 249-298) antibody
PCDHGA4 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Protocadherin gamma Subfamily A, 4 (PCDHGA4) (AA 1-931) antibodyPCDHGA4 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Protocadherin gamma Subfamily A, 4 (PCDHGA4) (N-Term) antibodyPCDHGA4 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Protocadherin gamma Subfamily A, 4 (PCDHGA4) antibodyPCDHGA4 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 820 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- Protocadherin gamma Subfamily A, 4 (PCDHGA4)
- 别名
- PCDHGA4 (PCDHGA4 产品)
- 别名
- PCDH-GAMMA-A4 antibody, Pcdhga3 antibody, protocadherin gamma subfamily A, 4 antibody, PCDHGA4 antibody, Pcdhga4 antibody
- 背景
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PCDHGA4 is a single-pass type I membrane protein. It contains 6 cadherin domains. PCDHGA4 is a potential calcium-dependent cell-adhesion protein. It may be involved in the establishment and maintenance of specific neuronal connections in the brain.This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes.
Alias Symbols: PCDH-GAMMA-A4
Protein Size: 820 - 分子量
- 86 kDa
- 基因ID
- 56111
- NCBI登录号
- NM_032053, NP_114442
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