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SULF2 抗体 (C-Term)

SULF2 适用: 人, 小鼠, 大鼠, 兔, Cow, 犬, 马, Pig WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2783715
发货至: 中国
  • 抗原 See all SULF2 抗体
    SULF2 (Sulfatase 2 (SULF2))
    抗原表位
    • 15
    • 9
    • 8
    • 7
    • 6
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 41
    • 18
    • 17
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠, 兔, Cow, 犬, 马, Pig
    宿主
    • 53
    • 3
    • 1
    克隆类型
    • 54
    • 3
    多克隆
    标记
    • 17
    • 8
    • 7
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SULF2 antibody is un-conjugated
    应用范围
    • 44
    • 25
    • 13
    • 13
    • 11
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    序列
    DVLNQLHVQL MELRSCKGYK QCNPRTRNMD LGLKDGGSYE QYRQFQRRKW
    预测反应
    Cow: 79%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 93%, Rabbit: 100%, Rat: 100%
    产品特性
    This is a rabbit polyclonal antibody against SULF2. It was validated on Western Blot and immunohistochemistry.
    纯化方法
    Protein A purified
    免疫原
    The immunogen is a synthetic peptide directed towards the C terminal region of human SULF2
    Top Product
    Discover our top product SULF2 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 870 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Uchimura, Morimoto-Tomita, Bistrup, Li, Lyon, Gallagher, Werb, Rosen: "HSulf-2, an extracellular endoglucosamine-6-sulfatase, selectively mobilizes heparin-bound growth factors and chemokines: effects on VEGF, FGF-1, and SDF-1." in: BMC biochemistry, Vol. 7, pp. 2, (2006) (PubMed).

  • 抗原
    SULF2 (Sulfatase 2 (SULF2))
    别名
    SULF2 (SULF2 产品)
    别名
    Sulf1 antibody, zgc:55612 antibody, SULF2 antibody, si:dkeyp-84g9.1 antibody, wu:fb48e04 antibody, HSULF-2 antibody, xtsulf2 antibody, 2010004N24Rik antibody, AU020235 antibody, MSulf-2 antibody, mKIAA1247 antibody, sulfatase 2a antibody, sulfatase 2 antibody, extracellular sulfatase Sulf-2 antibody, sulfatase 2b antibody, sulfatase 2 S homeolog antibody, sulf2a antibody, SULF2 antibody, LOC100540921 antibody, sulf2 antibody, sulf2b antibody, sulf2.S antibody, Sulf2 antibody
    背景
    Heparan sulfate proteoglycans (HSPGs) act as coreceptors for numerous heparin-binding growth factors and cytokines and are involved in cell signaling. Heparan sulfate 6-O-endosulfatases, such as SULF2, selectively remove 6-O-sulfate groups from heparan sulfate. This activity modulates the effects of heparan sulfate by altering binding sites for signaling molecules.Heparan sulfate proteoglycans (HSPGs) act as coreceptors for numerous heparin-binding growth factors and cytokines and are involved in cell signaling. Heparan sulfate 6-O-endosulfatases, such as SULF2, selectively remove 6-O-sulfate groups from heparan sulfate. This activity modulates the effects of heparan sulfate by altering binding sites for signaling molecules (Dai et al., 2005 [PubMed 16192265]).[supplied by OMIM].
    Alias Symbols: DKFZp313E091, FLJ90554, HSULF-2, KIAA1247, MGC126411
    Protein Interaction Partner: MYC, UBC,
    Protein Size: 870
    分子量
    98 kDa
    基因ID
    55959
    NCBI登录号
    NM_018837, NP_061325
    UniProt
    Q8IWU5
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