MAP3K2 抗体 (N-Term)
-
- 抗原 See all MAP3K2 抗体
- MAP3K2 (Mitogen-Activated Protein Kinase Kinase Kinase 2 (MAP3K2))
-
抗原表位
- N-Term
-
适用
- 人, 小鼠, 大鼠, 犬, 兔, Cow, 马, 豚鼠, Pig, 斑马鱼
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This MAP3K2 antibody is un-conjugated
-
应用范围
- Western Blotting (WB)
- 序列
- AERKKRLSII GPTSRDRSSP PPGYIPDELH QVARNGSFTS INSEGEFIPE
- 预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 92%, Horse: 80%, Human: 100%, Mouse: 86%, Pig: 100%, Rabbit: 93%, Rat: 93%, Zebrafish: 100%
- 产品特性
- This is a rabbit polyclonal antibody against MAP3K2. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human MAP3K2
- Top Product
- Discover our top product MAP3K2 Primary Antibody
-
-
- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
-
Antigen size: 619 AA
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
- 抗原
- MAP3K2 (Mitogen-Activated Protein Kinase Kinase Kinase 2 (MAP3K2))
- 别名
- MAP3K2 (MAP3K2 产品)
- 别名
- Mekk2 antibody, MEKK2 antibody, MEKK2B antibody, 9630061B06Rik antibody, AI585793 antibody, Mekk2b antibody, mitogen activated protein kinase kinase kinase 2 antibody, mitogen-activated protein kinase kinase kinase 2 antibody, Map3k2 antibody, MAP3K2 antibody
- 背景
-
MAP3K2 is a component of a protein kinase signal transduction cascade. It regulates the JNK and ERK5 pathways by phosphorylating and activating MAP2K5 and MAP2K7. It also plays a role in caveolae kiss-and-run dynamics.The protein encoded by this gene is a member of serine/threonine protein kinase family. This kinase preferentially activates other kinases involved in the MAP kinase signaling pathway. This kinase has been shown to directly phosphorylate and activate Ikappa B kinases, and thus plays a role in NF-kappa B signaling pathway. This kinase has also been found to bind and activate protein kinase C-related kinase 2, which suggests its involvement in a regulated signaling process. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-18 AF111105.1 37-54 19-79 AI760702.1 474-534 80-371 AF111105.1 116-407 372-2650 AB208963.1 313-2591 2651-3557 AK075004.1 2050-2956 3558-3571 BQ423724.1 71-84 3572-3577 W07290.1 11-16 3578-4302 AK074577.1 1-725 4303-4421 BM470563.1 21-139 4422-4424 AK074577.1 845-847 4425-4941 BM470563.1 142-658
Alias Symbols: MEKK2, MEKK2B
Protein Interaction Partner: MAP3K2, STAMBP, USP2, UBC, MAP2K7, MAP2K5, MAPK7, MAP3K3, XIAP, BIRC2, YWHAB, YWHAE, HSP90AA1, STK38, MAP2K4, MAP2K3, SMURF1, NEDD4, NEDD4L, Stub1, YWHAG, PIBF1, IKBKG, WNK1, SH2D2A, PKN2, MAP3K5, YWHAZ, MAPK8, NFKBIA, SFN,
Protein Size: 619 - 分子量
- 70 kDa
- 基因ID
- 10746
- NCBI登录号
- NM_006609, NP_006600
- UniProt
- Q9Y2U5
- 途径
- MAPK Pathway
-