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- 抗原 See all TTC8 抗体
- TTC8 (Tetratricopeptide Repeat Domain 8 (TTC8))
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠, Cow, 犬, 马, 兔, 豚鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TTC8 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- ENAIAQVPRP GTSLKLPGTN QTGGPSQAVR PITQAGRPIT GFLRPSTQSG
- 预测反应
- Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 86%, Human: 100%, Mouse: 93%, Rabbit: 86%, Rat: 100%
- 产品特性
- This is a rabbit polyclonal antibody against TTC8. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human TTC8
- Top Product
- Discover our top product TTC8 Primary Antibody
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anti-Tetratricopeptide Repeat Domain 8 (TTC8) (AA 416-514) antibody
TTC8 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 7E2 unconjugated
anti-Tetratricopeptide Repeat Domain 8 (TTC8) (AA 1-505) antibodyTTC8 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Tetratricopeptide Repeat Domain 8 (TTC8) (AA 251-330) antibodyTTC8 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IF (cc), IF (p), IHC (fro), IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Tetratricopeptide Repeat Domain 8 (TTC8) (AA 1-505) antibodyTTC8 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Tetratricopeptide Repeat Domain 8 (TTC8) (Internal Region) antibodyVerified TTC8 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Tetratricopeptide Repeat Domain 8 (TTC8) (AA 71-120) antibodyTTC8 适用: 人, 马, 兔, Hamster, 猴 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 475 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- TTC8 (Tetratricopeptide Repeat Domain 8 (TTC8))
- 别名
- TTC8 (TTC8 产品)
- 背景
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The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. This ciliogenic function is mediated in part by the Rab8 GDP/GTP exchange factor, which localizes to the basal body and contacts the BBSome. Rab8(GTP) enters the primary cilium and promotes extension of the ciliary membrane. Firstly the BBSome associates with the ciliary membrane and binds to Rabin8, the guanosyl exchange factor (GEF) for Rab8 and then the Rab8-GTP localizes to the cilium and promotes docking and fusion of carrier vesicles to the base of the ciliary membrane.This gene encodes a protein that has been directly linked to Bardet-Biedl syndrome. The primary features of this syndrome include retinal dystrophy, obesity, polydactyly, renal abnormalities and learning disabilities. Experimentation in non-human eukaryotes suggests that this gene is expressed in ciliated cells and that it is involved in the formation of cilia. Alternate transcriptional splice variants have been characterized.
Alias Symbols: BBS8, RP51
Protein Interaction Partner: UBC, PCM1,
Protein Size: 475 - 分子量
- 54 kDa
- 基因ID
- 123016
- NCBI登录号
- NM_198310, NP_938052
- 途径
- Hedgehog Signaling
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