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HS3ST5 抗体 (C-Term)

HS3ST5 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2783636
发货至: 中国
  • 抗原 See all HS3ST5 抗体
    HS3ST5 (Heparan Sulfate (Glucosamine) 3-O-Sulfotransferase 5 (HS3ST5))
    抗原表位
    C-Term
    适用
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔
    宿主
    • 3
    克隆类型
    • 3
    多克隆
    标记
    • 3
    This HS3ST5 antibody is un-conjugated
    应用范围
    • 3
    • 1
    Western Blotting (WB)
    序列
    SQYNLYFNAT RGFYCLRFNI IFNKCLAGSK GRIHPEVDPS VITKLRKFFH
    预测反应
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
    产品特性
    This is a rabbit polyclonal antibody against HS3ST5. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the C terminal region of human HS3ST5
    Top Product
    Discover our top product HS3ST5 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 346 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    HS3ST5 (Heparan Sulfate (Glucosamine) 3-O-Sulfotransferase 5 (HS3ST5))
    别名
    HS3ST5 (HS3ST5 产品)
    别名
    3-OST-5 antibody, 3OST5 antibody, HS3OST5 antibody, NBLA04021 antibody, D930005L05Rik antibody, Gm1151 antibody, Hs3ost5 antibody, HS3ST6 antibody, HS3ST5 antibody, heparan sulfate-glucosamine 3-sulfotransferase 5 antibody, heparan sulfate (glucosamine) 3-O-sulfotransferase 5 antibody, HS3ST5 antibody, Hs3st5 antibody, hs3st5 antibody
    背景
    HS3ST5 is the rate limiting enzyme for synthesis of HSact. It performs the crucial step modification in the biosynthesis of anticoagulant heparan sulfate (HSact) that is to complete the structure of the antithrombin pentasaccharide binding site. HS3ST5 also generates GlcUA-GlcNS or IdoUA-GlcNS and IdoUA2S-GlcNH2. The substrate-specific O-sulfation generates an enzyme-modified heparan sulfate which acts as a binding receptor to Herpes simplex virus-1 (HSV-1) and permits its entry.HS3ST5 belongs to a group of heparan sulfate 3-O-sulfotransferases (EC 2.8.2.23) that transfer sulfate from 3-prime-phosphoadenosine 5-prime phosphosulfate (PAPS) to heparan sulfate and heparin (Mochizuki et al., 2003 [PubMed 12740361]).[supplied by OMIM]. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-139 AL355498.10 32491-32629 c 140-2744 AL355498.10 25338-27942 c
    Alias Symbols: 3-OST-5, 3OST5, HS3OST5, NBLA04021
    Protein Size: 346
    分子量
    40 kDa
    基因ID
    222537
    NCBI登录号
    NM_153612, NP_705840
    UniProt
    Q8IZT8
    途径
    Glycosaminoglycan Metabolic Process
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