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LTC4S 抗体 (N-Term)

LTC4S 适用: 人, Cow, 犬, 豚鼠, 马, 小鼠, 大鼠, 兔, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2783616
发货至: 中国
  • 抗原 See all LTC4S 抗体
    LTC4S (Leukotriene C4 Synthase (LTC4S))
    抗原表位
    • 10
    • 7
    • 4
    • 1
    N-Term
    适用
    • 22
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    人, Cow, 犬, 豚鼠, 马, 小鼠, 大鼠, 兔, 斑马鱼
    宿主
    • 22
    克隆类型
    • 22
    多克隆
    标记
    • 9
    • 3
    • 3
    • 3
    • 2
    • 2
    This LTC4S antibody is un-conjugated
    应用范围
    • 17
    • 16
    • 1
    • 1
    • 1
    Western Blotting (WB)
    序列
    MKDEVALLAA VTLLGVLLQA YFSLQVISAR RAFRVSPPLT TGPPEFERVY
    预测反应
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 92%, Rabbit: 93%, Rat: 92%, Zebrafish: 85%
    产品特性
    This is a rabbit polyclonal antibody against LTC4S. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Protein A purified
    免疫原
    The immunogen is a synthetic peptide directed towards the N terminal region of human LTC4S
    Top Product
    Discover our top product LTC4S Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 150 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Tang, Sally, Lesko, Discepolo, Abadie, Ciszewski, Semrad, Guandalini, Kupfer, Jabri: "Cysteinyl leukotrienes mediate lymphokine killer activity induced by NKG2D and IL-15 in cytotoxic T cells during celiac disease." in: The Journal of experimental medicine, Vol. 212, Issue 10, pp. 1487-95, (2015) (PubMed).

  • 抗原
    LTC4S (Leukotriene C4 Synthase (LTC4S))
    别名
    LTC4S (leukotriene C4 synthase) (LTC4S) (LTC4S 产品)
    别名
    LTC4S antibody, ltc4s antibody, si:dkey-33h4.2 antibody, leukotriene C4 synthase antibody, leukotriene C4 synthase-like antibody, leukotriene C4 synthase, gene 1 antibody, Ltc4s antibody, LTC4S antibody, LTC4SL antibody, ltc4s.1 antibody, ltc4s antibody
    背景
    The MAPEG (Membrane Associated Proteins in Eicosanoid and Glutathione metabolism) family includes a number of human proteins, several of which are involved the production of leukotrienes. LTC4S is an enzyme that catalyzes the first step in the biosynthesis of cysteinyl leukotrienes, potent biological compounds derived from arachidonic acid. Leukotrienes have been implicated as mediators of anaphylaxis and inflammatory conditions such as human bronchial asthma.The MAPEG (Membrane Associated Proteins in Eicosanoid and Glutathione metabolism) family includes a number of human proteins, several of which are involved the production of leukotrienes. This gene encodes an enzyme that catalyzes the first step in the biosynthesis of cysteinyl leukotrienes, potent biological compounds derived from arachidonic acid. Leukotrienes have been implicated as mediators of anaphylaxis and inflammatory conditions such as human bronchial asthma. This protein localizes to the nuclear envelope and adjacent endoplasmic reticulum. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: MGC33147
    Protein Interaction Partner: MGST1, LTC4S, ALOX5AP, ALOX5,
    Protein Size: 150
    分子量
    16 kDa
    基因ID
    4056
    NCBI登录号
    NM_145867, NP_665874
    UniProt
    Q16873
    途径
    Cellular Response to Molecule of Bacterial Origin
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