CHST14 抗体 (Middle Region)
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- 抗原 See all CHST14 抗体
- CHST14 (Carbohydrate (N-Acetylgalactosamine 4-0) Sulfotransferase 14 (CHST14))
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抗原表位
- Middle Region
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适用
- 人, 小鼠, 大鼠, Pig, Cow, 犬, 豚鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CHST14 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- REYQQRYGAE IVRRYRAGAG PSPAGDDVTF PEFLRYLVDE DPERMNEHWM
- 预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 86%, Human: 100%, Mouse: 100%, Pig: 100%, Rat: 100%
- 产品特性
- This is a rabbit polyclonal antibody against CHST14. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human CHST14
- Top Product
- Discover our top product CHST14 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 338 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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The phenotype of the musculocontractural type of Ehlers-Danlos syndrome due to CHST14 mutations." in: American journal of medical genetics. Part A, Vol. 170A, Issue 1, pp. 103-15, (2016) (PubMed).
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The phenotype of the musculocontractural type of Ehlers-Danlos syndrome due to CHST14 mutations." in: American journal of medical genetics. Part A, Vol. 170A, Issue 1, pp. 103-15, (2016) (PubMed).
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- 抗原
- CHST14 (Carbohydrate (N-Acetylgalactosamine 4-0) Sulfotransferase 14 (CHST14))
- 别名
- CHST14 (CHST14 产品)
- 别名
- ATCS antibody, D4ST1 antibody, HNK1ST antibody, 2600016L03Rik antibody, D4ST-1 antibody, D4st1 antibody, d4st1 antibody, MGC136487 antibody, wu:fc04a01 antibody, zgc:136487 antibody, carbohydrate sulfotransferase 14 antibody, carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 14 antibody, CHST14 antibody, Chst14 antibody, chst14 antibody
- 背景
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CHST14 belongs to the sulfotransferase 2 family. CHST14 catalyzes the transfer of sulfate to position 4 of the N-acetylgalactosamine (GalNAc) residue of dermatan sulfate. It transfers sulfate to the C-4 hydroxyl of beta1,4-linked GalNAc that is substituted with an alpha-linked iduronic acid (IdoUA) at the C-3 hydroxyl. It transfers sulfate more efficiently to GalNAc residues in -IdoUA-GalNAc-IdoUA- than in -GlcUA-GalNAc-GlcUA-sequences. CHST14 has preference for partially desulfated dermatan sulfate. Addition of sulfate to GalNAc may occur immediately after epimerization of GlcUA to IdoUA.
Alias Symbols: D4ST-1, D4ST1, HD4ST, HNK1ST, ATCS
Protein Interaction Partner: UBD,
Protein Size: 338 - 分子量
- 35 kDa
- 基因ID
- 113189
- UniProt
- Q8NCH0
- 途径
- Glycosaminoglycan Metabolic Process
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