ALG2 抗体 (C-Term)
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- 抗原 See all ALG2 抗体
- ALG2 (Asparagine-Linked Glycosylation 2, alpha-1,3-Mannosyltransferase Homolog (ALG2))
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抗原表位
- C-Term
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适用
- 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, Saccharomyces cerevisiae, 山羊, 斑马鱼
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ALG2 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- QSDLGQYVTF LRSFSDKQKI SLLHSCTCVL YTPSNEHFGI VPLEAMYMQC
- 预测反应
- Cow: 100%, Dog: 93%, Goat: 86%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 100%, Zebrafish: 93%
- 产品特性
- This is a rabbit polyclonal antibody against ALG2. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human ALG2
- Top Product
- Discover our top product ALG2 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 416 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Congenital myasthenic syndromes due to mutations in ALG2 and ALG14." in: Brain : a journal of neurology, Vol. 136, Issue Pt 3, pp. 944-56, (2013) (PubMed).
: "A severe human metabolic disease caused by deficiency of the endoplasmatic mannosyltransferase hALG11 leads to congenital disorder of glycosylation-Ip." in: Human molecular genetics, Vol. 19, Issue 8, pp. 1413-24, (2010) (PubMed).
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Congenital myasthenic syndromes due to mutations in ALG2 and ALG14." in: Brain : a journal of neurology, Vol. 136, Issue Pt 3, pp. 944-56, (2013) (PubMed).
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- 抗原
- ALG2 (Asparagine-Linked Glycosylation 2, alpha-1,3-Mannosyltransferase Homolog (ALG2))
- 别名
- ALG2 (ALG2 产品)
- 别名
- CDGIi antibody, NET38 antibody, hALPG2 antibody, 1110018A23Rik antibody, 1300013N08Rik antibody, ALPG2 antibody, MNCb-5081 antibody, im:7145131 antibody, ALG2, alpha-1,3/1,6-mannosyltransferase antibody, asparagine-linked glycosylation 2 (alpha-1,3-mannosyltransferase) antibody, ALG2, alpha-1,3/1,6-mannosyltransferase L homeolog antibody, GDP-Man:Man(1)GlcNAc(2)-PP-dolichol alpha-1,3-mannosyltransferase antibody, ALG2 antibody, Alg2 antibody, alg2.L antibody, alg2 antibody
- 背景
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ALG2 is a member of the glycosyltransferase 1 family. It acts as an alpha 1,3 mannosyltransferase, mannosylating Man(2)GlcNAc(2)-dolichol diphosphate and Man(1)GlcNAc(2)-dolichol diphosphate to form Man(3)GlcNAc(2)-dolichol diphosphate. Defects in this gene have been associated with congenital disorder of glycosylation type Ih (CDG-Ii).This gene encodes a member of the glycosyltransferase 1 family. The encoded protein acts as an alpha 1,3 mannosyltransferase, mannosylating Man(2)GlcNAc(2)-dolichol diphosphate and Man(1)GlcNAc(2)-dolichol diphosphate to form Man(3)GlcNAc(2)-dolichol diphosphate. Defects in this gene have been associated with congenital disorder of glycosylation type Ih (CDG-Ii). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: CDGIi, FLJ14511, hALPG2, NET38
Protein Interaction Partner: UBC, PLSCR3, SHISA5, PDCD6IP, ALG2, VPS28, PTPN23, SEC31A, TSG101, LAMP1, HSP90AA1, PTK2B, ANXA11, ANXA7, VPS37A, PEF1, SRI,
Protein Size: 416 - 分子量
- 47 kDa
- 基因ID
- 85365
- NCBI登录号
- NM_033087, NP_149078
- UniProt
- Q9H553
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