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POLR3B 抗体 (C-Term)

POLR3B 适用: 人, 小鼠, 大鼠, 犬, Cow, 兔, 斑马鱼, 马, 豚鼠, Saccharomyces cerevisiae, 山羊 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2783516
发货至: 中国
  • 抗原 See all POLR3B 抗体
    POLR3B (Polymerase (RNA) III (DNA Directed) Polypeptide B (POLR3B))
    抗原表位
    • 7
    • 7
    • 6
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 27
    • 27
    • 8
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠, 犬, Cow, 兔, 斑马鱼, 马, 豚鼠, Saccharomyces cerevisiae, 山羊
    宿主
    • 37
    • 2
    克隆类型
    • 37
    • 2
    多克隆
    标记
    • 18
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This POLR3B antibody is un-conjugated
    应用范围
    • 27
    • 24
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB)
    序列
    IEKVMISSNA EDAFLIKMLL RQTRRPEIGD KFSSRHGQKG VCGLIVPQED
    预测反应
    Cow: 100%, Dog: 100%, Goat: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 93%, Zebrafish: 100%
    产品特性
    This is a rabbit polyclonal antibody against POLR3B. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the C terminal region of human POLR3B
    Top Product
    Discover our top product POLR3B Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 1133 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Yee, Gong, Huang, Lorent, Dolan, Maraia, Pack: "Mutation of RNA Pol III subunit rpc2/polr3b Leads to Deficiency of Subunit Rpc11 and disrupts zebrafish digestive development." in: PLoS biology, Vol. 5, Issue 11, pp. e312, (2007) (PubMed).

  • 抗原
    POLR3B (Polymerase (RNA) III (DNA Directed) Polypeptide B (POLR3B))
    别名
    POLR3B (POLR3B 产品)
    别名
    RGD1565311 antibody, C128 antibody, HLD8 antibody, RPC2 antibody, 2700078H01Rik antibody, A330032P03Rik antibody, C85372 antibody, RNA polymerase III subunit B antibody, polymerase (RNA) III (DNA directed) polypeptide B antibody, Polr3b antibody, POLR3B antibody
    背景
    POLR3B belongs to the RNA polymerase beta chain family. DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. POLR3B is the second largest core component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. It is proposed to contribute to the polymerase catalytic activity and forms the polymerase active center together with the largest subunit. Pol III is composed of mobile elements and RPC2 is part of the core element with the central large cleft and probably a clamp element that moves to open and close the cleft.
    Alias Symbols: FLJ10388, RPC2, C128, HLD8
    Protein Interaction Partner: SUMO2, UBC, POLR3H, TSR1, POLR1D, CRCP, POLR3A, POLR1C, POLR2H, POLR3D, RPAP2, RPAP1, GPN1, RAE1,
    Protein Size: 1133
    分子量
    128 kDa
    基因ID
    55703
    NCBI登录号
    NM_018082, NP_060552
    UniProt
    Q9NW08
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