POLR2H 抗体 (N-Term)
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- 抗原 See all POLR2H 抗体
- POLR2H (Polymerase (RNA) II (DNA Directed) Polypeptide H (POLR2H))
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠, Cow, 兔, 豚鼠, 马, 斑马鱼
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This POLR2H antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- DLGDKFRLVI ASTLYEDGTL DDGEYNPTDD RPSRADQFEY VMYGKVYRIE
- 预测反应
- Cow: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%
- 产品特性
- This is a rabbit polyclonal antibody against POLR2H. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Protein A purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human POLR2H
- Top Product
- Discover our top product POLR2H Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 150 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." in: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).
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Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." in: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).
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- 抗原
- POLR2H (Polymerase (RNA) II (DNA Directed) Polypeptide H (POLR2H))
- 别名
- POLR2H (POLR2H 产品)
- 别名
- RPABC3 antibody, RPB17 antibody, RPB8 antibody, POLR2H antibody, RGD1561203 antibody, rpb8 antibody, rpb17 antibody, hsrpb8 antibody, rpabc3 antibody, zgc:110289 antibody, RNA polymerase II subunit H antibody, polymerase (RNA) II (DNA directed) polypeptide H antibody, polymerase (RNA) II subunit H L homeolog antibody, polymerase (RNA) II subunit H antibody, info polymerase (RNA) II (DNA directed) polypeptide H antibody, POLR2H antibody, Polr2h antibody, polr2h.L antibody, polr2h antibody
- 背景
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POLR2H is one of the essential subunits of RNA polymerase II that is shared by the other two eukaryotic DNA-directed RNA polymerases, I and III.This gene encodes one of the essential subunits of RNA polymerase II that is shared by the other two eukaryotic DNA-directed RNA polymerases, I and III. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. This gene encodes a member of the E2F transcription factor protein family. E2F family members play a crucial role in control of the cell cycle and of the action of tumor suppressor proteins. They are also a target of the transforming proteins of small DNA tumor viruses. Many E2F proteins contain several evolutionarily conserved domains: a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. The encoded protein of this gene is atypical because it lacks the transactivation and tumor suppressor protein association domains. It contains a modular suppression domain and is an inhibitor of E2F-dependent transcription. The protein is part of a multimeric protein complex that contains a histone methyltransferase and the transcription factors Mga and Max. Multiple transcript variants have been reported for this gene, but it has not been clearly demonstrated that they encode valid isoforms. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-400 AU142999.1 1-400 401-907 BI772069.1 287-793 908-1792 BC008348.1 928-1812 1793-3185 AC099344.4 111461-112853 c
Alias Symbols: RPABC3, RPB17, RPB8, hsRPB8
Protein Interaction Partner: TCEB3, SRC, PSMB9, ESR1, CEP57, RNF2, SNRNP200, SART3, POLR2E, DNMT3B, DNMT3A, BAG3, POLR2C, MED19, METTL18, MED26, UBC, POLR3D, POLR3H, POLR3B, POLR1A, POLR3A, POLR1C, NEDD8, Atf7ip, SUMO2, INTS10, POLR2D, POLR2A, BRCA1, BARD1, INTS5, INTS3, INTS6, INTS1
Protein Size: 150 - 分子量
- 17 kDa
- 基因ID
- 5437
- NCBI登录号
- NM_006232, NP_006223
- UniProt
- P52434
- 途径
- Regulatory RNA Pathways
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