SPTLC2 抗体 (N-Term)
-
- 抗原 See all SPTLC2 抗体
- SPTLC2 (serine Palmitoyltransferase, Long Chain Base Subunit 2 (SPTLC2))
-
抗原表位
- N-Term
-
适用
- 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 兔, 斑马鱼, 马
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This SPTLC2 antibody is un-conjugated
-
应用范围
- Western Blotting (WB)
- 序列
- VLTYVGYGVL TLFGYLRDFL RYWRIEKCHH ATEREEQKDF VSLYQDFENF
- 预测反应
- Cow: 100%, Dog: 91%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
- 产品特性
- This is a rabbit polyclonal antibody against SPTLC2. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human SPTLC2
- Top Product
- Discover our top product SPTLC2 Primary Antibody
-
-
- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
-
Antigen size: 562 AA
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
- 抗原
- SPTLC2 (serine Palmitoyltransferase, Long Chain Base Subunit 2 (SPTLC2))
- 别名
- SPTLC2 (SPTLC2 产品)
- 背景
-
SPTLC2 is a long chain base subunit of serine palmitoyltransferase. Serine palmitoyltransferase, which consists of two different subunits, is the key enzyme in sphingolipid biosynthesis. It catalyzes the pyridoxal-5-prime-phosphate-dependent condensation of L-serine and palmitoyl-CoA to 3-oxosphinganine. Mutations in this gene were identified in patients with hereditary sensory neuropathy type I.This gene encodes a long chain base subunit of serine palmitoyltransferase. Serine palmitoyltransferase, which consists of two different subunits, is the key enzyme in sphingolipid biosynthesis. It catalyzes the pyridoxal-5-prime-phosphate-dependent condensation of L-serine and palmitoyl-CoA to 3-oxosphinganine. Mutations in this gene were identified in patients with hereditary sensory neuropathy type I. Alternatively spliced variants encoding different isoforms have been identified. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-973 AB011098.1 1-973 974-1108 BQ338973.1 306-440 1109-3679 AB011098.1 1109-3679 3680-4578 AB011098.1 3682-4580 4579-4876 BG024616.1 326-623 4877-6812 AB011098.1 4879-6814 6813-7189 W24363.1 55-431 7190-7250 BM992457.1 1-61 c
Alias Symbols: KIAA0526, LCB2, SPT2, HSN1C, LCB2A, NSAN1C, hLCB2a
Protein Interaction Partner: UBC, BCL6, SPTLC1,
Protein Size: 562 - 分子量
- 63 kDa
- 基因ID
- 9517
- NCBI登录号
- NM_004863, NP_004854
- UniProt
- O15270
-