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COQ8A 抗体 (N-Term)

COQ8A 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2783345
发货至: 中国
  • 抗原 See all COQ8A 抗体
    COQ8A (Coenzyme Q8A (COQ8A))
    抗原表位
    • 15
    • 8
    • 8
    • 8
    • 6
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 52
    • 31
    • 30
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, 斑马鱼
    宿主
    • 53
    • 13
    克隆类型
    • 53
    • 13
    多克隆
    标记
    • 26
    • 6
    • 5
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This COQ8A antibody is un-conjugated
    应用范围
    • 57
    • 32
    • 13
    • 13
    • 10
    • 7
    • 5
    • 4
    • 3
    • 1
    • 1
    Western Blotting (WB)
    序列
    FANPRDSFSA MGFQRRFFHQ DQSPVGGLTA EDIEKARQAK ARPENKQHKQ
    预测反应
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 90%
    产品特性
    This is a rabbit polyclonal antibody against CABC1. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the N terminal region of human CABC1
    Top Product
    Discover our top product COQ8A Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 647 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Lagier-Tourenne, Tazir, López, Quinzii, Assoum, Drouot, Busso, Makri, Ali-Pacha, Benhassine, Anheim, Lynch, Thibault, Plewniak, Bianchetti, Tranchant, Poch, DiMauro, Mandel, Barros, Hirano, Koenig: "ADCK3, an ancestral kinase, is mutated in a form of recessive ataxia associated with coenzyme Q10 deficiency." in: American journal of human genetics, Vol. 82, Issue 3, pp. 661-72, (2008) (PubMed).

  • 抗原
    COQ8A (Coenzyme Q8A (COQ8A))
    别名
    CABC1 (COQ8A 产品)
    别名
    ARCA2 antibody, CABC1 antibody, COQ10D4 antibody, COQ8 antibody, SCAR9 antibody, 4632432J16Rik antibody, AI462003 antibody, Cabc1 antibody, mKIAA0451 antibody, cabc1 antibody, Adck3 antibody, adck4 antibody, si:dkey-114g7.2 antibody, coenzyme Q8A antibody, aarF domain containing kinase 3 antibody, coenzyme Q8B antibody, COQ8A antibody, Coq8a antibody, coq8a antibody, ADCK3 antibody, coq8b antibody
    背景
    CABC1 is a mitochondrial protein similar to yeast ABC1, which functions in an electron-transferring membrane protein complex in the respiratory chain. It is not related to the family of ABC transporter proteins. Expression of this gene is induced by the tumor suppressor p53 and in response to DNA damage, and inhibiting its expression partially suppresses p53-induced apoptosis.This gene encodes a mitochondrial protein similar to yeast ABC1, which functions in an electron-transferring membrane protein complex in the respiratory chain. It is not related to the family of ABC transporter proteins. Expression of this gene is induced by the tumor suppressor p53 and in response to DNA damage, and inhibiting its expression partially suppresses p53-induced apoptosis. Alternatively spliced transcript variants have been found, however, their full-length nature has not been determined.
    Alias Symbols: ADCK3, COQ8, MGC4849, ARCA2, CABC1, SCAR9
    Protein Interaction Partner: TMEM239, REEP6, TMEM159, AGTRAP, TFIP11, RABAC1, VCP, UBC, IRAK2, IRAK1, ICT1, COQ8,
    Protein Size: 647
    分子量
    72 kDa
    基因ID
    56997
    NCBI登录号
    NM_020247, NP_064632
    UniProt
    Q8NI60
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