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Prohibitin 2 抗体 (C-Term)

PHB2 适用: 人, 小鼠, 大鼠, 兔, 豚鼠, Cow, 犬, Pig WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2783329
发货至: 中国
  • 抗原 See all Prohibitin 2 (PHB2) 抗体
    Prohibitin 2 (PHB2)
    抗原表位
    • 16
    • 8
    • 8
    • 8
    • 7
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 75
    • 39
    • 14
    • 10
    • 7
    • 7
    • 6
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠, 兔, 豚鼠, Cow, 犬, Pig
    宿主
    • 73
    • 2
    • 2
    克隆类型
    • 74
    • 3
    多克隆
    标记
    • 47
    • 4
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Prohibitin 2 antibody is un-conjugated
    应用范围
    • 66
    • 24
    • 22
    • 18
    • 17
    • 13
    • 13
    • 10
    • 10
    • 9
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    序列
    KLRKIRAAQN ISKTIATSQN RIYLTADNLV LNLQDESFTR GSDSLIKGKK
    预测反应
    Cow: 100%, Dog: 93%, Guinea Pig: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%
    产品特性
    This is a rabbit polyclonal antibody against PHB2. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the C terminal region of human PHB2
    Top Product
    Discover our top product PHB2 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 299 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    Prohibitin 2 (PHB2)
    别名
    PHB2 (PHB2 产品)
    别名
    bcap37 antibody, zgc:73150 antibody, wu:fc28c08 antibody, PHB2 antibody, phb2 antibody, ATPHB2 antibody, F21M11.21 antibody, F21M11_21 antibody, prohibitin 2 antibody, DKFZp469N1310 antibody, BAP antibody, BCAP37 antibody, Bap37 antibody, PNAS-141 antibody, REA antibody, p22 antibody, bap37 antibody, prohibitin2 antibody, xphb2 antibody, AU044498 antibody, Bcap37 antibody, Bap antibody, Bap-37 antibody, Bcap27 antibody, prohibitin 2a antibody, prohibitin 2 antibody, prohibitin 2 S homeolog antibody, phb2a antibody, PHB2 antibody, phb2 antibody, phb2.S antibody, Phb2 antibody
    背景
    PHB2 acts as a mediator of transcriptional repression by nuclear hormone receptors via recruitment of histone deacetylases (By similarity). It functions as an estrogen receptor (ER)-selective coregulator that potentiates the inhibitory activities of antiestrogens and represses the activity of estrogens. PHB2 competes with NCOA1 for modulation of ER transcriptional activity. It probably involved in regulating mitochondrial respiration activity and in aging.
    Alias Symbols: BAP, BCAP37, Bap37, MGC117268, PNAS-141, REA, p22
    Protein Interaction Partner: HUWE1, IGF1R, HDAC1, ESR1, KIAA1244, NCOR1, SUMO2, STAU1, UBC, MDM2, ASB14, ASB17, SUZ12, EED, RNF2, UPF2, ADRB2, CDK2, env, VCAM1, TEAD3, ITGA4, ILF3, FN1, ATF2, C1QBP, AFP, UBL4A, EPAS1, FMNL1, PAXIP1, MDC1, MYOD1, MEF2A, FHL2, ECT2, BRCA1, AKT1, Htt, U
    Protein Size: 299
    分子量
    33 kDa
    基因ID
    11331
    NCBI登录号
    NM_007273, NP_009204
    UniProt
    Q99623
    途径
    Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling
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