BAG3 抗体 (Middle Region)
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- 抗原 See all BAG3 抗体
- BAG3 (BCL2-Associated Athanogene 3 (BAG3))
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抗原表位
- Middle Region
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适用
- 人, 小鼠, 大鼠, Cow, 豚鼠, 兔, 马, 犬
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This BAG3 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- NVTRPAAQPS FHQAQKTHYP AQQGEYQTHQ PVYHKIQGDD WEPRPLRAAS
- 预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
- 产品特性
- This is a rabbit polyclonal antibody against BAG3. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human BAG3
- Top Product
- Discover our top product BAG3 Primary Antibody
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anti-BCL2-Associated Athanogene 3 (BAG3) antibody
BAG3 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Associated Athanogene 3 (BAG3) (C-Term) antibodyVerified BAG3 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-BCL2-Associated Athanogene 3 (BAG3) (AA 380-575) antibodyBAG3 适用: 人 WB, IHC, IP, IF 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Associated Athanogene 3 (BAG3) antibodyBAG3 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Associated Athanogene 3 (BAG3) (C-Term) antibodyBAG3 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Associated Athanogene 3 (BAG3) (AA 220-420) antibodyBAG3 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Associated Athanogene 3 (BAG3) antibodyBAG3 适用: 人 WB, ELISA, IHC 宿主: 兔 Monoclonal 3D8 unconjugated Recombinant Antibody
anti-BCL2-Associated Athanogene 3 (BAG3) (AA 1-575) antibodyBAG3 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-BCL2-Associated Athanogene 3 (BAG3) (AA 1-575) antibodyBAG3 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 5A8 unconjugated
anti-BCL2-Associated Athanogene 3 (BAG3) (AA 2-577) antibodyBAG3 适用: 小鼠 ELISA, IP 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 575 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- BAG3 (BCL2-Associated Athanogene 3 (BAG3))
- 别名
- BAG3 (BAG3 产品)
- 别名
- bag3-A antibody, MGC53113 antibody, zgc:100859 antibody, BAG3 antibody, ATBAG3 antibody, BCL-2-associated athanogene 3 antibody, T28J14.160 antibody, T28J14_160 antibody, BAG-3 antibody, BIS antibody, CAIR-1 antibody, MFM6 antibody, AA407278 antibody, Bis antibody, mg638 antibody, BCL2 associated athanogene 3 L homeolog antibody, BCL2-associated athanogene 3 antibody, BCL2 associated athanogene 3 antibody, BCL-2-associated athanogene 3 antibody, Bcl2-associated athanogene 3 antibody, bag3.L antibody, bag3 antibody, BAG3 antibody, Bag3 antibody
- 背景
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BAG3 inhibits the chaperone activity of HSP70/HSC70 by promoting substrate release. BAG3 has anti-apoptotic activity.BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The protein encoded by this gene contains a WW domain in the N-terminal region and a BAG domain in the C-terminal region. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: BAG-3, BIS, CAIR-1, MGC104307
Protein Interaction Partner: SF3B4, DAZAP2, ARRDC3, LITAF, MAGED1, PDE9A, HSPA8, PHLDB1, HSPB1, HSF1, STUB1, DNAJB6, AMOT, PDLIM7, MLF2, HSPB8, WBP2, UBC, MCM7, HSP90AB1, ETFA, MVP, ACLY, PSAP, PSME1, PSMD12, PSMD9, PSMD8, PSMD5, PSMD3, PSMD2, PSMC5, PSMC3, PSMC2, PSMC1, PSMB5, PSMB4
Protein Size: 575 - 分子量
- 61 kDa
- 基因ID
- 9531
- NCBI登录号
- NM_004281, NP_004272
- UniProt
- O95817
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