APEH 抗体 (N-Term)
-
- 抗原 See all APEH 抗体
- APEH (N-Acylaminoacyl-Peptide Hydrolase (APEH))
-
抗原表位
- N-Term
-
适用
- 人, 小鼠, 大鼠, 豚鼠, 兔, Cow, 马, 斑马鱼, 犬
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This APEH antibody is un-conjugated
-
应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 序列
- VYEDDCFGCL SWSHSETHLL YVAEKKRPKA ESFFQTKALD VSASDDEIAR
- 预测反应
- Cow: 100%, Dog: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 83%
- 产品特性
- This is a rabbit polyclonal antibody against APEH. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human APEH
- Top Product
- Discover our top product APEH Primary Antibody
-
-
- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
-
Antigen size: 732 AA
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
- 抗原
- APEH (N-Acylaminoacyl-Peptide Hydrolase (APEH))
- 别名
- APEH (APEH 产品)
- 别名
- AARE antibody, ACPH antibody, APH antibody, D3F15S2 antibody, D3S48E antibody, DNF15S2 antibody, OPH antibody, AAP antibody, cb5 antibody, sb:cb5 antibody, wu:fi37d02 antibody, acylaminoacyl-peptide hydrolase antibody, acylpeptide hydrolase antibody, APEH antibody, Apeh antibody, apeh antibody
- 背景
-
APEH is the enzyme acylpeptide hydrolase, which catalyzes the hydrolysis of the terminal acetylated amino acid preferentially from small acetylated peptides. The acetyl amino acid formed by this hydrolase is further processed to acetate and a free amino acid by an aminoacylase. This gene is located within the same region of chromosome 3 (3p21) as the aminoacylase gene, and deletions at this locus are also associated with a decrease in aminoacylase activity. The acylpeptide hydrolase is a homotetrameric protein of 300 kDa with each subunit consisting of 732 amino acid residues. It can play an important role in destroying oxidatively damaged proteins in living cells. Deletions of this gene locus are found in various types of carcinomas, including small cell lung carcinoma and renal cell carcinoma.This gene encodes the enzyme acylpeptide hydrolase, which catalyzes the hydrolysis of the terminal acetylated amino acid preferentially from small acetylated peptides. The acetyl amino acid formed by this hydrolase is further processed to acetate and a free amino acid by an aminoacylase. This gene is located within the same region of chromosome 3 (3p21) as the aminoacylase gene, and deletions at this locus are also associated with a decrease in aminoacylase activity. The acylpeptide hydrolase is a homotetrameric protein of 300 kDa with each subunit consisting of 732 amino acid residues. It can play an important role in destroying oxidatively damaged proteins in living cells. Deletions of this gene locus are found in various types of carcinomas, including small cell lung carcinoma and renal cell carcinoma. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: ACPH, APH, D3F15S2, D3S48E, DNF15S2, MGC2178, OPH, AARE
Protein Interaction Partner: IST1, UBC, LGALS8, APEH, SNX6, CAND1, TOLLIP, CYHR1, JMJD6, HSPA4L, IPO7, DNM1L, VPS26A, NMI, H1FX, ZYX, TBCD, TARS, STAT1, SHMT2, SHMT1, PPM1G, SERPINE2, PAWR, LAMP2, KARS, HIST1H1C, GARS, CTTN, CARS, PREPL, SHBG, UBA5, TMEM62,
Protein Size: 732 - 分子量
- 81 kDa
- 基因ID
- 327
- NCBI登录号
- NM_001640, NP_001631
- UniProt
- P13798
-