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P4HB 抗体 (C-Term)

Name: P4HB 抗体 (C-Term)
SKU: ABIN2783246
Availability: OutOfStock

P4HB 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, Pig, 兔, 马 WB, IHC 宿主: 兔 Polyclonal unconjugated

WB Suggested Anti-P4HB Antibody Titration: 0. (P4HB 抗体 (C-Term))

Host: Mouse Target Name: P4HB Sample Tissue: Mouse Small Intestine Antibody Dilution: 1ug/ml (P4HB 抗体 (C-Term))

P4HB antibody - C-terminal region Formalin Fixed Paraffin Embedded Tissue: Human Liver Tissue Observed Staining: Cytoplasm in hepatocytes Primary Antibody Concentration: 1:100 Secondary Antibody: Donkey anti-Rabbit-Cy3 Secondary Antibody Concentration: 1:200 Magnification: 20X Exposure Time: 0. (P4HB 抗体 (C-Term))

IHC

P4HB antibody - C-terminal region Formalin Fixed Paraffin Embedded Tissue: Human Lung Tissue Observed Staining: Cytoplasm of pneumocytes Primary Antibody Concentration: 1:600 Secondary Antibody: Donkey anti-Rabbit-Cy3 Secondary Antibody Concentration: 1:200 Magnification: 20X Exposure Time: 0. (P4HB 抗体 (C-Term))

IHC

4 images

(1 reference)

产品编号 ABIN2783246

发货至: 中国

Datasheet as PDF

抗原 See all P4HB 抗体

P4HB (Prolyl 4-Hydroxylase, beta Polypeptide (P4HB))
抗原表位
21

19

15

13

11

5

4

4

3

3

2

2

2

2

1

1

1

1

1

1

1

1

1

1
C-Term
适用
105

75

65

23

21

20

19

17

17

16

10

10

7

7

6

4

3

1

1

1
人, 小鼠, 大鼠, Cow, 犬, 豚鼠, Pig, 兔, 马
宿主
116

26

2
兔
Compatible Secondaries
克隆类型
110

34
多克隆
标记
60

16

15

9

4

3

3

3

3

3

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1
This P4HB antibody is un-conjugated
应用范围
110

66

44

43

43

37

18

15

14

13

13

5

5

2

1

1

1

1
Western Blotting (WB), Immunohistochemistry (IHC)

序列

DRTVIDYNGE RTLDGFKKFL ESGGQDGAGD DDDLEDLEEA EEPDMEEDDD

预测反应

Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%

产品特性

This is a rabbit polyclonal antibody against P4HB. It was validated on Western Blot using a cell lysate as a positive control.

纯化方法

Affinity Purified

免疫原

The immunogen is a synthetic peptide directed towards the C terminal region of human P4HB

Top Product

Discover our top product P4HB Primary Antibody
anti-Prolyl 4-Hydroxylase, beta Polypeptide (P4HB) (AA 1-508) antibody
P4HB 适用: 人 WB, IP, IF 宿主: 兔 Polyclonal unconjugated

anti-Prolyl 4-Hydroxylase, beta Polypeptide (P4HB) antibody
P4HB 适用: 人 WB, IHC, FACS 宿主: 兔 Polyclonal unconjugated

anti-Prolyl 4-Hydroxylase, beta Polypeptide (P4HB) antibody
P4HB 适用: 人 WB, IF, ICC, IHC (p), IEM 宿主: 兔 Polyclonal unconjugated

anti-Prolyl 4-Hydroxylase, beta Polypeptide (P4HB) (N-Term) antibody
P4HB 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 兔, 马 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Prolyl 4-Hydroxylase, beta Polypeptide (P4HB) (AA 329-508) antibody
P4HB 适用: 人 WB, IHC, IP, IF 宿主: 兔 Polyclonal unconjugated

anti-Prolyl 4-Hydroxylase, beta Polypeptide (P4HB) (AA 1-508) antibody
P4HB 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated

anti-Prolyl 4-Hydroxylase, beta Polypeptide (P4HB) (AA 409-509) antibody
P4HB 适用: 大鼠 WB, IHC, IP, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Prolyl 4-Hydroxylase, beta Polypeptide (P4HB) (AA 499-509) antibody
P4HB 适用: 人, 小鼠, 大鼠, Hamster, Cow, 犬, 豚鼠, 猴, Pig, 绵羊, 兔, 非洲爪蟾, 小鸡 WB, IHC, ICC, IHC (p) 宿主: 小鼠 Monoclonal unconjugated

anti-Prolyl 4-Hydroxylase, beta Polypeptide (P4HB) (AA 409-509) antibody (HRP)
P4HB 适用: 大鼠 WB, IHC, IP, IF, ICC 宿主: 兔 Polyclonal HRP

anti-Prolyl 4-Hydroxylase, beta Polypeptide (P4HB) (AA 409-509) antibody (FITC)
P4HB 适用: 大鼠 WB, IHC, IP, IF, ICC 宿主: 兔 Polyclonal FITC

应用备注

Optimal working dilutions should be determined experimentally by the investigator.

说明

Antigen size: 508 AA

限制

仅限研究用
状态

Liquid

浓度

Lot specific

缓冲液

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freeze-thaw cycles.

储存条件

-20 °C

储存方法

For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." in: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).
抗原

P4HB (Prolyl 4-Hydroxylase, beta Polypeptide (P4HB))

别名

P4HB (P4HB 产品)

别名

DSI antibody, ERBA2L antibody, GIT antibody, P4Hbeta antibody, PDI antibody, PDIA1 antibody, PHDB antibody, PO4DB antibody, PO4HB antibody, PROHB antibody, PDA2 antibody, PDIP antibody, PDIR antibody, ERp59 antibody, Pdia1 antibody, Thbp antibody, p55 antibody, XPDIp antibody, pdi antibody, 1810041F13Rik antibody, AI661267 antibody, Pdip antibody, Pdipl antibody, p58 antibody, prolyl 4-hydroxylase subunit beta antibody, protein disulfide isomerase family A member 2 antibody, prolyl 4-hydroxylase, beta polypeptide antibody, protein disulfide isomerase family A member 2 L homeolog antibody, protein disulfide isomerase associated 2 antibody, prolyl 4-hydroxylase subunit beta L homeolog antibody, protein disulfide-isomerase antibody, P4HB antibody, PDIA2 antibody, P4hb antibody, pdia2.L antibody, Pdia2 antibody, p4hb.L antibody, LOC8281065 antibody

背景

P4HB is the beta subunit of prolyl 4-hydroxylase, a highly abundant multifunctional enzyme that belongs to the protein disulfide isomerase family. When present as a tetramer consisting of two alpha and two beta subunits, this enzyme is involved in hydroxylation of prolyl residues in preprocollagen. This enzyme is also a disulfide isomerase containing two thioredoxin domains that catalyze the formation, breakage and rearrangement of disulfide bonds. Other known functions include its ability to act as a chaperone that inhibits aggregation of misfolded proteins in a concentration-dependent manner, its ability to bind thyroid hormone, its role in both the influx and efflux of S-nitrosothiol-bound nitric oxide, and its function as a subunit of the microsomal triglyceride transfer protein complex.This gene encodes the beta subunit of prolyl 4-hydroxylase, a highly abundant multifunctional enzyme that belongs to the protein disulfide isomerase family. When present as a tetramer consisting of two alpha and two beta subunits, this enzyme is involved in hydroxylation of prolyl residues in preprocollagen. This enzyme is also a disulfide isomerase containing two thioredoxin domains that catalyze the formation, breakage and rearrangement of disulfide bonds. Other known functions include its ability to act as a chaperone that inhibits aggregation of misfolded proteins in a concentration-dependent manner, its ability to bind thyroid hormone, its role in both the influx and efflux of S-nitrosothiol-bound nitric oxide, and its function as a subunit of the microsomal triglyceride transfer protein complex. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: DSI, ERBA2L, GIT, PDI, PDIA1, PHDB, PO4DB, PO4HB, PROHB, P4Hbeta
Protein Interaction Partner: P4HB, UBC, AGO2, MDM2, SUZ12, RNF2, EZH2, BMI1, rev, ACAA2, PLIN3, UBA2, USP5, TPD52L2, PSMD9, PFDN2, CLNS1A, TCEAL4, P3H1, UBQLN2, PABPC1, CALU, PARK2, HNRNPD, EGFR, UBD, BAG3, CXCR4, env, UBL4A, CSNK2A2, ATF2, GRDX, TMED9, GANAB, CCT4, CCT7, PDIA6, PDIA
Protein Size: 508

分子量

55 kDa

基因ID

5034

NCBI登录号

NM_000918, NP_000909

UniProt

P07237

途径

Maintenance of Protein Location, Cell RedoxHomeostasis, Lipid Metabolism