PDHA1 抗体 (C-Term)
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- 抗原 See all PDHA1 抗体
- PDHA1 (Pyruvate Dehydrogenase (Lipoamide) alpha 1 (PDHA1))
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抗原表位
- C-Term
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适用
- 人, 小鼠, 大鼠, Cow, 犬, Pig, 斑马鱼, 兔, 豚鼠, 马
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PDHA1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 82%
- 产品特性
- This is a rabbit polyclonal antibody against PDHA1. It was validated on Western Blot using a cell lysate as a positive control.
- 免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human PDHA1
- Top Product
- Discover our top product PDHA1 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 390 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- PDHA1 (Pyruvate Dehydrogenase (Lipoamide) alpha 1 (PDHA1))
- 别名
- PDHA1 (PDHA1 产品)
- 别名
- PDHA antibody, PDHCE1A antibody, PHE1A antibody, Pdha-1 antibody, pdha antibody, phe1a antibody, pdhce1a antibody, im:6895726 antibody, pdha1 antibody, wu:fd18b01 antibody, wu:fo96f03 antibody, zgc:73271 antibody, zgc:86692 antibody, Pdha1 antibody, wu:fp73b04 antibody, zgc:92705 antibody, NI36_05250 antibody, pdha1-a antibody, pdha1-b antibody, pyruvate dehydrogenase E1 alpha 1 subunit antibody, pyruvate dehydrogenase E1 alpha 1 antibody, pyruvate dehydrogenase (lipoamide) alpha 1 antibody, pyruvate dehydrogenase (lipoamide) alpha 1 pseudogene antibody, 2-oxo acid dehydrogenase antibody, pyruvate dehydrogenase (acetyl-transferring) E1 component subunit alpha antibody, pyruvate dehydrogenase alpha subunit protein antibody, pyruvate dehydrogenase (acetyl-transferring) protein, alpha subunit antibody, precursor of dehydrogenase pyruvate dehydrogenase E1 component alpha subunit antibody, pyruvate dehydrogenase antibody, pyruvate dehydrogenase E1 alpha 1 subunit a antibody, pyruvate dehydrogenase E1 alpha 1 subunit b antibody, pyruvate dehydrogenase E1 component subunit alpha antibody, pyruvate dehydrogenase (lipoamide) alpha 1 S homeolog antibody, PDHA1 antibody, Pdha1 antibody, pdha1 antibody, LOC719277 antibody, VNG_RS07485 antibody, RR_RS04695 antibody, pdhA1 antibody, pdha1a antibody, pdha1b antibody, NI36_RS05240 antibody, pdha1.S antibody
- 背景
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The pyruvate dehydrogenase complex is a nuclear-encoded mitochondrial matrix multienzyme complex that provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle by catalyzing the irreversible conversion of pyruvate into acetyl-CoA. The PDH complex is composed of multiple copies of 3 enzymes: E1 (PDHA1), dihydrolipoyl transacetylase (DLAT), and dihydrolipoyl dehydrogenase (DLD). The E1 enzyme is a heterotetramer of 2 alpha and 2 beta subunits. The E1-alpha subunit contains the E1 active site and plays a key role in the function of the PDH complex.The pyruvate dehydrogenase complex is a nuclear-encoded mitochondrial matrix multienzyme complex that provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle by catalyzing the irreversible conversion of pyruvate into acetyl-CoA. The PDH complex is composed of multiple copies of 3 enzymes: E1 (PDHA1), dihydrolipoyl transacetylase (DLAT, MIM 608770) (E2, EC 2.3.1.12), and dihydrolipoyl dehydrogenase (DLD, MIM 238331) (E3, EC 1.8.1.4). The E1 enzyme is a heterotetramer of 2 alpha and 2 beta subunits. The E1-alpha subunit contains the E1 active site and plays a key role in the function of the PDH complex (Brown et al., 1994 [PubMed 7853374]).[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: PDHA, PDHCE1A, PHE1A
Protein Interaction Partner: HUWE1, SUMO2, UBC, GINS4, DCPS, NCDN, VCL, PPP1R2, MSN, ASL, ADRB2, ITGA4, HNRNPDL, PDHX, SDHA, PDHB, OGDH, GTF2I, DLAT, CUL3, SIRT7, ATG101, WDR20, BABAM1, USP19, PDP1, EIF6, PDK4, PDK3, PDK2, PDK1, PDHA1, DGKE,
Protein Size: 390 - 分子量
- 40 kDa
- 基因ID
- 5160
- NCBI登录号
- NM_000284, NP_000275
- UniProt
- P08559
- 途径
- Warburg Effect
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