EIF4A1 抗体 (Middle Region)
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- 抗原 See all EIF4A1 抗体
- EIF4A1 (Eukaryotic Translation Initiation Factor 4A1 (EIF4A1))
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抗原表位
- Middle Region
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适用
- 人, 大鼠, 小鼠, 豚鼠, 马, 兔, 斑马鱼, Cow, 犬, 绵羊, Saccharomyces cerevisiae
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This EIF4A1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- TMPSDVLEVT KKFMRDPIRI LVKKEELTLE GIRQFYINVE REEWKLDTLC
- 预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 93%, Yeast: 92%, Zebrafish: 100%
- 产品特性
- This is a rabbit polyclonal antibody against EIF4A1. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human EIF4A1
- Top Product
- Discover our top product EIF4A1 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 406 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Cap-proximal nucleotides via differential eIF4E binding and alternative promoter usage mediate translational response to energy stress." in: eLife, Vol. 6, (2017) (PubMed).
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Cap-proximal nucleotides via differential eIF4E binding and alternative promoter usage mediate translational response to energy stress." in: eLife, Vol. 6, (2017) (PubMed).
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- 抗原
- EIF4A1 (Eukaryotic Translation Initiation Factor 4A1 (EIF4A1))
- 别名
- EIF4A1 (EIF4A1 产品)
- 别名
- DDX2A antibody, EIF-4A antibody, EIF4A antibody, eIF-4A-I antibody, eIF4A-I antibody, BM-010 antibody, Ddx2a antibody, Eif4 antibody, ddx2a antibody, eif-4a antibody, eif4a antibody, eif4a1 antibody, fb49a04 antibody, im:7143023 antibody, wu:fb20a10 antibody, wu:fb49a04 antibody, wu:fc76a02 antibody, wu:fc96c01 antibody, wu:fd15g03 antibody, eukaryotic translation initiation factor 4A1 antibody, eukaryotic translation initiation factor 4A1 L homeolog antibody, eukaryotic initiation factor 4A-I antibody, eukaryotic translation initiation factor 4A1A antibody, EIF4A1 antibody, Eif4a1 antibody, eif4a1.L antibody, eif4a1 antibody, LOC695050 antibody, eif4a1a antibody
- 背景
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EIF4A1 is an ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon.
Alias Symbols: DDX2A, EIF-4A, EIF4A, eIF4A-I, eIF-4A-I
Protein Interaction Partner: HUWE1, UBC, FUS, SUMO2, SUMO3, STAU1, MDM2, SH3RF2, TRAP1, FBXO6, ADRB2, CD81, NPM1, VCAM1, ITGA4, FN1, ESR1, LIG4, RPLP0P6, TMEM43, NDUFB11, ZBTB43, GPRC5A, EIF4G3, EIF4H, VDAC3, UQCRFS1, SDHA, RPS26, RPL19, RPL8, RPSA, ILF2, HSP90AB1, HSPA5, EIF4G2, EIF
Protein Size: 406 - 分子量
- 46 kDa
- 基因ID
- 1973
- NCBI登录号
- NM_001416, NP_001407
- UniProt
- P60842
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