REC8 抗体 (N-Term)
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- 抗原 See all REC8 抗体
- REC8 (REC8 Homolog (Yeast) (REC8))
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This REC8 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- QLQIGVIRVY SQQCQYLVED IQHILERLHR AQLQIRIDME TELPSLLLPN
- 预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rat: 100%
- 产品特性
- This is a rabbit polyclonal antibody against REC8. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human REC8
- Top Product
- Discover our top product REC8 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 547 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- REC8 (REC8 Homolog (Yeast) (REC8))
- 别名
- REC8 (REC8 产品)
- 别名
- Rec8L1 antibody, mrec antibody, HR21spB antibody, REC8L1 antibody, Rec8p antibody, REC8 meiotic recombination protein antibody, REC8 homolog (yeast) antibody, REC8 antibody, Rec8 antibody
- 背景
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REC8 is required during meiosis for separation of sister chromatids and homologous chromosomes. Proteolytic cleavage of REC8 on chromosome arms by separin during anaphase I allows for homologous chromosome separation in meiosis I and cleavage of REC8 on centromeres during anaphase II allows for sister chromatid separation in meiosis II.This gene encodes a member of the kleisin family of SMC (structural maintenance of chromosome) protein partners. The protein localizes to the axial elements of chromosomes during meiosis in both oocytes and spermatocytes. In the mouse, the homologous protein is a key component of the meiotic cohesion complex, which regulates sister chromatid cohesion and recombination between homologous chromosomes. Multiple alternatively spliced variants, encoding the same protein, have been found for this gene.
Alias Symbols: HR21spB, MGC950, REC8L1, Rec8p
Protein Interaction Partner: SYCP3, SMC3, SMC1A,
Protein Size: 547 - 分子量
- 62 kDa
- 基因ID
- 9985
- NCBI登录号
- NM_005132, NP_005123
- UniProt
- O95072
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