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ADCY10 抗体 (N-Term)

ADCY10 适用: 人, 大鼠, 小鼠, 兔, 犬, Cow, 豚鼠, 马 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2782970
发货至: 中国
  • 抗原 See all ADCY10 抗体
    ADCY10 (Adenylate Cyclase 10 (Soluble) (ADCY10))
    抗原表位
    • 15
    • 7
    • 6
    • 6
    • 6
    • 2
    • 2
    • 1
    N-Term
    适用
    人, 大鼠, 小鼠, 兔, 犬, Cow, 豚鼠, 马
    宿主
    • 35
    克隆类型
    • 35
    多克隆
    标记
    • 9
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ADCY10 antibody is un-conjugated
    应用范围
    • 20
    • 19
    • 13
    • 13
    • 12
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB)
    序列
    VGHTVRHEYT VIGQKVNLAA RMMMYYPGIV TCDSVTYNGS NLPAYFFKEL
    预测反应
    Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
    产品特性
    This is a rabbit polyclonal antibody against SAC. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the N terminal region of human SAC
    Top Product
    Discover our top product ADCY10 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 1610 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Corredor, Trakhtenberg, Pita-Thomas, Jin, Hu, Goldberg: "Soluble adenylyl cyclase activity is necessary for retinal ganglion cell survival and axon growth." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 32, Issue 22, pp. 7734-44, (2012) (PubMed).

  • 抗原
    ADCY10 (Adenylate Cyclase 10 (Soluble) (ADCY10))
    别名
    SAC (ADCY10 产品)
    别名
    HCA2 antibody, RP1-313L4.2 antibody, SAC antibody, SACI antibody, Sacy antibody, Sac antibody, 4930431D04Rik antibody, 4931412F17 antibody, sAC antibody, ADCY10 antibody, SACY antibody, adenylate cyclase 10 antibody, adenylate cyclase 10 (soluble) antibody, ADCY10 antibody, Adcy10 antibody
    背景
    SAC belongs to a distinct class of mammalian adenylyl cyclase that is soluble and insensitive to G protein or forskolin regulation. It is localized in the cytoplasm and is thought to function as a general bicarbonate sensor throughout the body. It may also play an important role in the generation of cAMP in spermatozoa, implying possible roles in sperm maturation through the epididymis, capacitation, hypermotility, and/or the acrosome reaction.The protein encoded by this gene belongs to a distinct class of mammalian adenylyl cyclase that is soluble and insensitive to G protein or forskolin regulation. It is localized in the cytoplasm and is thought to function as a general bicarbonate sensor throughout the body. It may also play an important role in the generation of cAMP in spermatozoa, implying possible roles in sperm maturation through the epididymis, capacitation, hypermotility, and/or the acrosome reaction. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: HCA2, RP1-313L4.2, SACI, SAC, Sacy
    Protein Interaction Partner: PTGIR, SSTR5,
    Protein Size: 1610
    分子量
    187 kDa
    基因ID
    55811
    NCBI登录号
    NM_018417, NP_060887
    UniProt
    Q96PN6
    途径
    cAMP Metabolic Process
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