KIRREL 抗体 (Middle Region)
(1 reference)-
- 抗原 See all KIRREL (NEPH1) 抗体
- KIRREL (NEPH1) (Kin of IRRE Like 1 (NEPH1))
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抗原表位
- Middle Region
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适用
- 人, 大鼠, 小鼠, 马, Cow, 犬, 兔, 豚鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This KIRREL antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- FLEVGTLERY TVERTNSGSG VLSTLTINNV MEADFQTHYN CTAWNSFGPG
- 预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
- 产品特性
- This is a rabbit polyclonal antibody against KIRREL. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human KIRREL
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anti-Kin of IRRE Like 1 (NEPH1) antibody
NEPH1 适用: 大鼠, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Kin of IRRE Like 1 (NEPH1) (AA 432-481) antibodyNEPH1 适用: 人, 大鼠, 小鼠, 马, Cow, 犬, 兔, 豚鼠, Hamster, 猴, Bat, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Kin of IRRE Like 1 (NEPH1) (AA 17-200) antibodyNEPH1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 757 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "Glycoprotein hyposialylation gives rise to a nephrotic-like syndrome that is prevented by sialic acid administration in GNE V572L point-mutant mice." in: PLoS ONE, Vol. 7, Issue 1, pp. e29873, (2012) (PubMed).
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: "Glycoprotein hyposialylation gives rise to a nephrotic-like syndrome that is prevented by sialic acid administration in GNE V572L point-mutant mice." in: PLoS ONE, Vol. 7, Issue 1, pp. e29873, (2012) (PubMed).
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- 抗原
- KIRREL (NEPH1) (Kin of IRRE Like 1 (NEPH1))
- 别名
- KIRREL (NEPH1 产品)
- 别名
- NEPH1 antibody, 6720469N11Rik antibody, Kirrel1 antibody, Neph1 antibody, nephrin related antibody, kirre like nephrin family adhesion molecule 1 antibody, kin of IRRE like (Drosophila) antibody, Smp_104390 antibody, Smp_140170 antibody, KIRREL1 antibody, Kirrel antibody, Kirrel1 antibody
- 背景
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KIRREL (NEPH1) is a member of the nephrin-like protein family, which includes NEPH2 and NEPH3. The cytoplasmic domains of these proteins interact with the C terminus of podocin (NPHS2), and the genes are expressed in kidney podocytes, cells involved in ensuring size- and charge-selective ultrafiltration. NEPH1 is a member of the nephrin-like protein family, which includes NEPH2 (MIM 607761) and NEPH3 (MIM 607762). The cytoplasmic domains of these proteins interact with the C terminus of podocin (NPHS2, MIM 604766), and the genes are expressed in kidney podocytes, cells involved in ensuring size- and charge-selective ultrafiltration (Sellin et al., 2003 [PubMed 12424224]).[supplied by OMIM]. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-337 AY302131.1 1-337 338-3211 BC109193.1 1-2874 3212-3609 AK001707.1 1904-2301 3610-3628 BC082969.1 2273-2291
Alias Symbols: FLJ10845, MGC129542, MGC129543, NEPH1
Protein Interaction Partner: UBC, SAV1, LATS1, GRB2, KIRREL, NPHS2, NPHS1, TJP1,
Protein Size: 757 - 分子量
- 84 kDa
- 基因ID
- 55243
- NCBI登录号
- NM_018240, NP_060710
- UniProt
- Q96J84
- 途径
- Regulation of Actin Filament Polymerization
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