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COQ2 抗体 (Middle Region)

COQ2 适用: 人, 小鼠, 大鼠, Pig, 兔, Saccharomyces cerevisiae, 斑马鱼, 犬, 山羊, 马 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2782857
发货至: 中国
  • 抗原 See all COQ2 抗体
    COQ2 (Coenzyme Q2 Homolog, Prenyltransferase (COQ2))
    抗原表位
    • 1
    • 1
    • 1
    Middle Region
    适用
    人, 小鼠, 大鼠, Pig, 兔, Saccharomyces cerevisiae, 斑马鱼, 犬, 山羊, 马
    宿主
    • 3
    • 2
    克隆类型
    • 3
    • 2
    多克隆
    标记
    • 5
    This COQ2 antibody is un-conjugated
    应用范围
    • 4
    • 3
    Western Blotting (WB)
    序列
    FSGVMWTLIY DTIYAHQDKR DDVLIGLKST ALRFGENTKP WLSGFSVAML
    预测反应
    Dog: 93%, Goat: 79%, Horse: 79%, Human: 100%, Mouse: 86%, Pig: 86%, Rabbit: 93%, Rat: 86%, Yeast: 91%, Zebrafish: 86%
    产品特性
    This is a rabbit polyclonal antibody against COQ2. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the middle region of human COQ2
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 384 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Sasaki, Kotoh, Watadani, Matsumoto: "New animal models reveal that coenzyme Q2 (Coq2) and placenta-specific 8 (Plac8) are candidate genes for the onset of type 2 diabetes associated with obesity in rats." in: Mammalian genome : official journal of the International Mammalian Genome Society, Vol. 26, Issue 11-12, pp. 619-29, (2015) (PubMed).

  • 抗原
    COQ2 (Coenzyme Q2 Homolog, Prenyltransferase (COQ2))
    别名
    COQ2 (COQ2 产品)
    别名
    CG9613 antibody, COQ2 antibody, Dmel\\CG9613 antibody, coq2 antibody, sbo antibody, CL640 antibody, COQ10D1 antibody, MSA1 antibody, RGD1306722 antibody, zgc:162600 antibody, 2310002F18Rik antibody, Coenzyme Q biosynthesis protein 2 antibody, coenzyme Q2, polyprenyltransferase antibody, coenzyme Q2 4-hydroxybenzoate polyprenyltransferase antibody, 4-hydroxybenzoate polyprenyltransferase, mitochondrial antibody, Coq2 antibody, COQ2 antibody, coq2 antibody, coq-2 antibody
    背景
    COQ2 catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. COQ2 mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB.CoQ (ubiquinone) serves as a redox carrier in the mitochondrial respiratory chain and is a lipid-soluble antioxidant. COQ2, or parahydroxybenzoate-polyprenyltransferase (EC 2.5.1.39), catalyzes one of the final reactions in the biosynthesis of CoQ, the prenylation of parahydroxybenzoate with an all-trans polyprenyl group (Forsgren et al., 2004 [PubMed 15153069]).[supplied by OMIM]. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-90 BC020728.1 1-90 91-96 BG699931.1 80-85 97-789 BC020728.1 97-789 790-792 BQ363759.1 169-171 793-1535 BC020728.1 793-1535 1536-1554 BC008804.2 1496-1514
    Alias Symbols: CL640, FLJ26072
    Protein Interaction Partner: UBC,
    Protein Size: 384
    分子量
    42 kDa
    基因ID
    27235
    NCBI登录号
    NM_015697, NP_056512
    UniProt
    Q96H96
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