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- 抗原 See all PCDHA4 抗体
- PCDHA4 (Protocadherin alpha 4 (PCDHA4))
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抗原表位
- C-Term
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适用
- 人, 豚鼠, 大鼠, Cow, 犬, 马, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PCDHA4 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- SGYNAWLSYE LQPETASASI PFRVGLYTGE ISTTRALDET DAPRQRLLVL
- 预测反应
- Cow: 93%, Dog: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 93%, Rat: 93%
- 产品特性
- This is a rabbit polyclonal antibody against PCDHA4. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human PCDHA4
- Top Product
- Discover our top product PCDHA4 Primary Antibody
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anti-Protocadherin alpha 4 (PCDHA4) (AA 1-947) antibody
PCDHA4 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Protocadherin alpha 4 (PCDHA4) (AA 601-650) antibodyPCDHA4 适用: 人, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Protocadherin alpha 4 (PCDHA4) (AA 110-159) antibodyPCDHA4 适用: 人, 豚鼠, 大鼠, Cow, 犬, 马, 小鼠, 兔, Bat, 小鸡, 猴, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-Protocadherin alpha 4 (PCDHA4) (N-Term) antibodyPCDHA4 适用: 人, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Protocadherin alpha 4 (PCDHA4) (C-Term) antibodyPCDHA4 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 947 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- PCDHA4 (Protocadherin alpha 4 (PCDHA4))
- 别名
- PCDHA4 (PCDHA4 产品)
- 别名
- CNR1 antibody, CNRN1 antibody, CRNR1 antibody, PCDH-ALPHA4 antibody, Cnr1 antibody, Crnr1 antibody, R75250 antibody, PCDHA4 antibody, CNRv4 antibody, Pcdha4 antibody, protocadherin alpha 4 antibody, protocadherin alpha-4 antibody, PCDHA4 antibody, Pcdha4 antibody, LOC100713594 antibody, LOC100629843 antibody
- 背景
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The gene encoding PCDHA4 is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. PCDHA4 is a single-pass type I membrane protein. It contains 6 cadherin domains. PCDHA4 is a potential calcium-dependent cell-adhesion protein. It may be involved in the establishment and maintenance of specific neuronal connections in the brain.This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined.
Alias Symbols: CNR1, CNRN1, CRNR1, MGC138307, MGC142169, PCDH-ALPHA4
Protein Interaction Partner: SGTA, LRIF1, CCDC90B, RBM48, IGSF21, SETDB1, C14orf1, UNC119, GDF9, RELN, TLE1, TP53, GAPDH, EEF1A1, APLP1,
Protein Size: 947 - 分子量
- 99 kDa
- 基因ID
- 56144
- NCBI登录号
- NM_018907, NP_061730
- UniProt
- Q9UN74
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