UGT1A4 抗体 (N-Term)
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- 抗原 See all UGT1A4 抗体
- UGT1A4 (UDP Glucuronosyltransferase 1 Family, Polypeptide A4 (UGT1A4))
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抗原表位
- N-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This UGT1A4 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- VVLTPEVNMH IKEEKFFTLT AYAVPWTQKE FDRVTLGYTQ GFFETEHLLK
- 预测反应
- Human: 100%
- 产品特性
- This is a rabbit polyclonal antibody against UGT1A4. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human UGT1A4
- Top Product
- Discover our top product UGT1A4 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 534 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- UGT1A4 (UDP Glucuronosyltransferase 1 Family, Polypeptide A4 (UGT1A4))
- 别名
- UGT1A4 (UGT1A4 产品)
- 别名
- HUG-BR2 antibody, UDPGT antibody, UDPGT 1-4 antibody, UGT-1D antibody, UGT1-04 antibody, UGT1.4 antibody, UGT1D antibody, UGT1 antibody, UGT1A4 antibody, UDP glucuronosyltransferase family 1 member A4 antibody, UDP-glucuronosyltransferase 1-4 antibody, UGT1A4 antibody, UGT1-4 antibody
- 背景
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UGT1A4 is an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, hormones, and drugs, into water-soluble, excretable metabolites. This enzyme has some glucuronidase activity towards amines, steroids, and sapogenins. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter.
Alias Symbols: HUG-BR2, UDPGT, UGT1D, UGT-1D, UGT1.4, UGT1-04, UDPGT 1-4
Protein Interaction Partner: CYB5A,
Protein Size: 534 - 分子量
- 57 kDa
- 基因ID
- 54657
- NCBI登录号
- NM_007120, NP_009051
- UniProt
- P22310
- 途径
- Steroid Hormone Biosynthesis, Regulation of Lipid Metabolism by PPARalpha
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