Melanoma gp100 抗体 (N-Term)
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- 抗原 See all Melanoma gp100 (PMEL) 抗体
- Melanoma gp100 (PMEL) (Premelanosome Protein (PMEL))
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抗原表位
- N-Term
- 适用
- 人, 马, 大鼠, 小鼠, 犬, Cow, 山羊, 豚鼠, 兔
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Melanoma gp100 antibody is un-conjugated
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应用范围
- Immunohistochemistry (IHC), Western Blotting (WB)
- 序列
- HFLRNQPLTF ALQLHDPSGY LAEADLSYTW DFGDSSGTLI SRALVVTHTY
- 预测反应
- Cow: 93%, Dog: 86%, Goat: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 86%, Rat: 93%
- 产品特性
- This is a rabbit polyclonal antibody against SILV. It was validated on Western Blot and immunohistochemistry.
- 纯化方法
- Protein A purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human SILV
- Top Product
- Discover our top product PMEL Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 661 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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A lumenal domain-dependent pathway for sorting to intralumenal vesicles of multivesicular endosomes involved in organelle morphogenesis." in: Developmental cell, Vol. 10, Issue 3, pp. 343-54, (2006) (PubMed).
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A lumenal domain-dependent pathway for sorting to intralumenal vesicles of multivesicular endosomes involved in organelle morphogenesis." in: Developmental cell, Vol. 10, Issue 3, pp. 343-54, (2006) (PubMed).
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- 抗原
- Melanoma gp100 (PMEL) (Premelanosome Protein (PMEL))
- 别名
- SILV (PMEL 产品)
- 别名
- D12S53E antibody, ME20 antibody, ME20-M antibody, ME20M antibody, P1 antibody, P100 antibody, PMEL17 antibody, SI antibody, SIL antibody, SILV antibody, gp100 antibody, D10H12S53E antibody, D12S53Eh antibody, Pmel17 antibody, Si antibody, Silv antibody, gp87 antibody, RPE1 antibody, MMP115 antibody, silverb antibody, silver antibody, cb397 antibody, fdv antibody, pmel17 antibody, sb:cb397 antibody, silva antibody, wu:fc11g11 antibody, wu:fj24g11 antibody, zgc:136622 antibody, premelanosome protein antibody, premelanosome protein b antibody, premelanosome protein a antibody, PMEL antibody, Pmel antibody, pmelb antibody, pmela antibody
- 背景
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SILV could be a melanogenic enzyme. It could represent an oncofetal self-antigen that is normally expressed at low levels in quiescent adult melanocytes but overexpressed by proliferating neonatal melanocytes and during tumor growth. Release of the soluble form, ME20-S, it could protect tumor cells from antibody mediated immunity.
Alias Symbols: D12S53E, ME20, PMEL17, SI, SIL, gp100, P1, P100, SILV, ME20M, ME20-M
Protein Size: 661 - 分子量
- 70 kDa
- 基因ID
- 6490
- NCBI登录号
- NM_006928, NP_008859
- UniProt
- P40967
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