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Melanoma gp100 抗体 (N-Term)

PMEL 适用: 人, 马, 大鼠, 小鼠, 犬, Cow, 山羊, 豚鼠, 兔 IHC, WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2782746
发货至: 中国
  • 抗原 See all Melanoma gp100 (PMEL) 抗体
    Melanoma gp100 (PMEL) (Premelanosome Protein (PMEL))
    抗原表位
    • 7
    • 7
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    N-Term
    适用
    人, 马, 大鼠, 小鼠, 犬, Cow, 山羊, 豚鼠, 兔
    宿主
    • 47
    • 36
    • 1
    克隆类型
    • 48
    • 36
    • 1
    多克隆
    标记
    • 46
    • 6
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Melanoma gp100 antibody is un-conjugated
    应用范围
    • 41
    • 39
    • 34
    • 33
    • 21
    • 14
    • 8
    • 5
    • 2
    • 2
    • 1
    Immunohistochemistry (IHC), Western Blotting (WB)
    序列
    HFLRNQPLTF ALQLHDPSGY LAEADLSYTW DFGDSSGTLI SRALVVTHTY
    预测反应
    Cow: 93%, Dog: 86%, Goat: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 86%, Rat: 93%
    产品特性
    This is a rabbit polyclonal antibody against SILV. It was validated on Western Blot and immunohistochemistry.
    纯化方法
    Protein A purified
    免疫原
    The immunogen is a synthetic peptide directed towards the N terminal region of human SILV
    Top Product
    Discover our top product PMEL Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 661 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Theos, Truschel, Tenza, Hurbain, Harper, Berson, Thomas, Raposo, Marks: "A lumenal domain-dependent pathway for sorting to intralumenal vesicles of multivesicular endosomes involved in organelle morphogenesis." in: Developmental cell, Vol. 10, Issue 3, pp. 343-54, (2006) (PubMed).

  • 抗原
    Melanoma gp100 (PMEL) (Premelanosome Protein (PMEL))
    别名
    SILV (PMEL 产品)
    背景
    SILV could be a melanogenic enzyme. It could represent an oncofetal self-antigen that is normally expressed at low levels in quiescent adult melanocytes but overexpressed by proliferating neonatal melanocytes and during tumor growth. Release of the soluble form, ME20-S, it could protect tumor cells from antibody mediated immunity.
    Alias Symbols: D12S53E, ME20, PMEL17, SI, SIL, gp100, P1, P100, SILV, ME20M, ME20-M
    Protein Size: 661
    分子量
    70 kDa
    基因ID
    6490
    NCBI登录号
    NM_006928, NP_008859
    UniProt
    P40967
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