WNT6 抗体 (Middle Region)
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- 抗原 See all WNT6 抗体
- WNT6 (Wingless-Type MMTV Integration Site Family, Member 6 (WNT6))
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抗原表位
- Middle Region
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适用
- 人, 小鼠, 大鼠, 兔, Cow, 犬, 豚鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This WNT6 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- ERFHGASRVM GTNDGKALLP AVRTLKPPGR ADLLYAADSP DFCAPNRRTG
- 预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
- 产品特性
- This is a rabbit polyclonal antibody against WNT6. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human WNT6
- Top Product
- Discover our top product WNT6 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 365 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- WNT6 (Wingless-Type MMTV Integration Site Family, Member 6 (WNT6))
- 别名
- WNT6 (WNT6 产品)
- 别名
- WNT6 antibody, si:dkey-31m21.2 antibody, Wnt6 antibody, AA409270 antibody, Wnt-6 antibody, Xwnt-6 antibody, wnt-6 antibody, wnt6-A antibody, xWnt6 antibody, Wnt family member 6 antibody, wingless-type MMTV integration site family, member 6b antibody, wingless-type MMTV integration site family, member 6 antibody, Wnt family member 6 S homeolog antibody, WNT6 antibody, Wnt6 antibody, wnt6b antibody, wnt6.S antibody
- 背景
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The WNT family consists of several secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. WNT6 is overexpressed in cervical cancer cell line and strongly coexpressed with another family member, WNT10A, in colorectal cancer cell line. The WNT6 protein overexpression may play key roles in carcinogenesis. The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It is overexpressed in cervical cancer cell line and strongly coexpressed with another family member, WNT10A, in colorectal cancer cell line. The gene overexpression may play key roles in carcinogenesis. This gene and the WNT10A gene are clustered in the chromosome 2q35 region. The protein encoded by this gene is 97 % identical to the mouse Wnt6 protein at the amino acid level.
Alias Symbols: -
Protein Interaction Partner: PORCN,
Protein Size: 365 - 分子量
- 37 kDa
- 基因ID
- 7475
- NCBI登录号
- NM_006522, NP_006513
- UniProt
- Q9Y6F9
- 途径
- WNT signaling, Tube Formation
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