ZMPSTE24 抗体 (N-Term)
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- 抗原 See all ZMPSTE24 (Zmpste24) 抗体
- ZMPSTE24 (Zmpste24) (Zinc Metalloproteinase, Ste24 (Zmpste24))
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠, 兔, Cow, 马, 斑马鱼, 犬, 豚鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ZMPSTE24 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- LYSETEGTLI LLFGGIPYLW RLSGRFCGYA GFGPEYEITQ SLVFLLLATL
- 预测反应
- Cow: 100%, Dog: 93%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 79%, Rabbit: 100%, Rat: 91%, Zebrafish: 90%
- 产品特性
- This is a rabbit polyclonal antibody against ZMPSTE24. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human ZMPSTE24
- Top Product
- Discover our top product Zmpste24 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 475 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- ZMPSTE24 (Zmpste24) (Zinc Metalloproteinase, Ste24 (Zmpste24))
- 别名
- ZMPSTE24 (Zmpste24 产品)
- 别名
- DDBDRAFT_0189115 antibody, DDBDRAFT_0237846 antibody, DDB_0189115 antibody, DDB_0237846 antibody, F2N1.21 antibody, F2N1_21 antibody, STE24 antibody, FACE-1 antibody, FACE1 antibody, HGPS antibody, PRO1 antibody, Ste24p antibody, A530043O15Rik antibody, D030046F19 antibody, Face-1 antibody, MADB antibody, fi45a02 antibody, wu:fi45a02 antibody, zgc:55655 antibody, zinc metallopeptidase STE24 antibody, zinc metallopeptidase STE24 L homeolog antibody, CAAX prenyl protease antibody, Peptidase family M48 family protein antibody, zinc metallopeptidase, STE24 antibody, zinc metallopeptidase, STE24 homolog antibody, ZMPSTE24 antibody, zmpste24.L antibody, zmpste24 antibody, ATSTE24 antibody, Zmpste24 antibody
- 背景
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ZMPSTE24 is a member of the peptidase M48A family. This protein is a zinc metalloproteinase involved in the two step post-translational proteolytic cleavage of carboxy terminal residues of farnesylated prelamin A to form mature lamin A. Mutations in ZMPSTE24 gene have been associated with mandibuloacral dysplasia and restrictive dermopathy.The protein encoded by this gene is a zinc metalloprotease similar to yeast Ste24p. It is an integral membrane protein belonging to peptidase family M48 and is found in the endoplasmic reticulum and possibly in the Golgi compartment. It is thought to be involved in the proteolytic processing of farnesylated proteins.
Alias Symbols: FACE-1, FACE1, FLJ14968, STE24, Ste24p, HGPS, PRO1
Protein Interaction Partner: UBC, BAG3, KIAA2013, TMEM43, MRPL40, MRPS5, SYNJ2BP, ATP6V1H, HNRNPUL1, RAB10, VDAC1, UQCRFS1P1, S100A10, RAB5C, PTPN1, NDUFB7, MGST3, HNRNPF, GALNT2, DDOST, CD55, ELAVL1, MME,
Protein Size: 475 - 分子量
- 55 kDa
- 基因ID
- 10269
- NCBI登录号
- NM_005857, NP_005848
- UniProt
- O75844
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