LMAN1 抗体 (N-Term)
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- 抗原 See all LMAN1 抗体
- LMAN1 (Lectin, Mannose-Binding, 1 (LMAN1))
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠, 犬, Pig, 兔, Cow, 斑马鱼, 马, 豚鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This LMAN1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- DPAVALPHRR FEYKYSFKGP HLVQSDGTVP FWAHAGNAIP SSDQIRVAPS
- 预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 93%
- 产品特性
- This is a rabbit polyclonal antibody against LMAN1. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human LMAN1
- Top Product
- Discover our top product LMAN1 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 510 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- LMAN1 (Lectin, Mannose-Binding, 1 (LMAN1))
- 别名
- LMAN1 (LMAN1 产品)
- 别名
- ERGIC-53 antibody, ERGIC53 antibody, F5F8D antibody, FMFD1 antibody, MCFD1 antibody, MR60 antibody, gp58 antibody, 2610020P13Rik antibody, AI326273 antibody, AU043785 antibody, C730041J05 antibody, P58 antibody, p58 antibody, LMAN1 antibody, cpx-iii antibody, cpxiii antibody, lman1 antibody, wu:fc54c09 antibody, wu:fi36e01 antibody, Xp58 antibody, lman1-a antibody, lectin, mannose binding 1 antibody, lectin, mannose-binding, 1 antibody, complexin 3 antibody, lectin, mannose binding 1 S homeolog antibody, LMAN1 antibody, Lman1 antibody, cplx3 antibody, lman1 antibody, lman1.S antibody
- 背景
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LMAN1 is a type I integral membrane protein localized in the intermediate region between the endoplasmic reticulum and the Golgi, presumably recycling between the two compartments. The protein is a mannose-specific lectin and is a member of a novel family of plant lectin homologs in the secretory pathway of animal cells. Mutations in its gene are associated with a coagulation defect. Using positional cloning, its gene was identified as the disease gene leading to combined factor V-factor VIII deficiency, a rare, autosomal recessive disorder in which both coagulation factors V and VIII are diminished.The protein encoded by this gene is a type I integral membrane protein localized in the intermediate region between the endoplasmic reticulum and the Golgi, presumably recycling between the two compartments. The protein is a mannose-specific lectin and is a member of a novel family of plant lectin homologs in the secretory pathway of animal cells. Mutations in the gene are associated with a coagulation defect. Using positional cloning, the gene was identified as the disease gene leading to combined factor V-factor VIII deficiency, a rare, autosomal recessive disorder in which both coagulation factors V and VIII are diminished. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: ERGIC-53, ERGIC53, F5F8D, FMFD1, MCFD1, MR60, gp58
Protein Interaction Partner: UBC, NEDD8, YIPF3, env, PIGS, TMED2, YBX1, HSP90AA1, HNRNPU, APP, UBXN6, RAB3GAP2, RAB3GAP1, COPE, TUBB4B, TUBB3, COPB2, VCP, DNAJC7, P4HB, HSPA8, HSPA1A, COPB1, COPA, BCAP29, BCAP31, HLA-A, CANX, ELAVL1, MCFD2, F8,
Protein Size: 510 - 分子量
- 54 kDa
- 基因ID
- 3998
- NCBI登录号
- NM_005570, NP_005561
- UniProt
- P49257
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