COX15 抗体 (N-Term)
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- 抗原 See all COX15 抗体
- COX15 (Cytochrome C Oxidase Assembly Homolog 15 (COX15))
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抗原表位
- N-Term
- 适用
- 人, 大鼠, 小鼠, 兔, 犬, 斑马鱼, Cow, Saccharomyces cerevisiae, 豚鼠, 马
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This COX15 antibody is un-conjugated
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应用范围
- Immunohistochemistry (IHC), Western Blotting (WB)
- 序列
- DWHLIKEMKP PTSQEEWEAE FQRYQQFPEF KILNHDMTLT EFKFIWYMEY
- 预测反应
- Cow: 93%, Dog: 86%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 86%, Rat: 93%, Yeast: 82%, Zebrafish: 79%
- 产品特性
- This is a rabbit polyclonal antibody against COX15. It was validated on Western Blot and immunohistochemistry.
- 纯化方法
- Protein A purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human COX15
- Top Product
- Discover our top product COX15 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 388 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Analysis of Oligomerization Properties of Heme a Synthase Provides Insights into Its Function in Eukaryotes." in: The Journal of biological chemistry, Vol. 291, Issue 19, pp. 10411-25, (2016) (PubMed).
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Analysis of Oligomerization Properties of Heme a Synthase Provides Insights into Its Function in Eukaryotes." in: The Journal of biological chemistry, Vol. 291, Issue 19, pp. 10411-25, (2016) (PubMed).
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- 抗原
- COX15 (Cytochrome C Oxidase Assembly Homolog 15 (COX15))
- 别名
- COX15 (COX15 产品)
- 别名
- COX15 antibody, wu:fa18g06 antibody, zgc:56240 antibody, zgc:77422 antibody, 2900026G05Rik antibody, CEMCOX2 antibody, COX15, cytochrome c oxidase assembly homolog antibody, COX15 homolog, cytochrome c oxidase assembly protein (yeast) antibody, COX15 cytochrome c oxidase assembly homolog antibody, cytochrome c oxidase assembly homolog 15 (yeast) antibody, cytochrome c oxidase assembly protein 15 antibody, cytochrome c oxidase assembly protein COX15 homolog antibody, COX15 antibody, Cox15 antibody, cox15 antibody, LOC100410987 antibody, LOC100599631 antibody
- 背景
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Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes a protein which is not a structural subunit, but may be essential for the biogenesis of COX formation and may function in the hydroxylation of heme O, according to the yeast mutant studies. This protein is predicted to contain 5 transmembrane domains localized in the mitochondrial inner membrane.Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes a protein which is not a structural subunit, but may be essential for the biogenesis of COX formation and may function in the hydroxylation of heme O, according to the yeast mutant studies. This protein is predicted to contain 5 transmembrane domains localized in the mitochondrial inner membrane. Alternative splicing of this gene generates several transcript variants diverging in the 3' region including alternate poly A sites. In total, 2 different isoforms are encoded by these variants.
Alias Symbols: -
Protein Interaction Partner: UBC, CLN3, MRPS14, NDUFA12, TOMM7, MRPL15, LAMTOR3, SURF1, NDUFS8, NDUFS6, NDUFS4, NDUFA9, CYC1,
Protein Size: 388 - 分子量
- 44 kDa
- 基因ID
- 1355
- NCBI登录号
- NM_004376, NP_004367
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