ADAM15 抗体 (Middle Region)
-
- 抗原 See all ADAM15 抗体
- ADAM15 (ADAM Metallopeptidase Domain 15 (ADAM15))
-
抗原表位
- Middle Region
-
适用
- 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, Pig, 兔
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This ADAM15 antibody is un-conjugated
-
应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 序列
- QPAAPLCLQT ANTRGNAFGS CGRNPSGSYV SCTPRDAICG QLQCQTGRTQ
- 预测反应
- Cow: 86%, Dog: 79%, Guinea Pig: 79%, Horse: 85%, Human: 100%, Mouse: 100%, Pig: 85%, Rabbit: 79%, Rat: 100%
- 产品特性
- This is a rabbit polyclonal antibody against ADAM15. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human ADAM15
- Top Product
- Discover our top product ADAM15 Primary Antibody
-
-
- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
-
Antigen size: 862 AA
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
- 抗原
- ADAM15 (ADAM Metallopeptidase Domain 15 (ADAM15))
- 别名
- ADAM15 (ADAM15 产品)
- 别名
- ADAM15 antibody, mdc15 antibody, MDC15 antibody, metargidin antibody, tMDCVI antibody, ADAM metallopeptidase domain 15 antibody, ADAM metallopeptidase domain 15 L homeolog antibody, a disintegrin and metallopeptidase domain 15 (metargidin) antibody, ADAM15 antibody, adam15.L antibody, adam15 antibody, Adam15 antibody
- 背景
-
ADAM15 is a member of the ADAM (a disintegrin and metalloproteinase) protein family. ADAM family members are type I transmembrane glycoproteins known to be involved in cell adhesion and proteolytic ectodomain processing of cytokines and adhesion molecules. This protein contains multiple functional domains including a zinc-binding metalloprotease domain, a disintegrin-like domain, as well as a EGF-like domain. Through its disintegrin-like domain, this protein specifically interacts with the integrin beta chain, beta 3. It also interacts with Src family protein-tyrosine kinases in a phosphorylation-dependent manner, suggesting that this protein may function in cell-cell adhesion as well as in cellular signaling.The protein encoded by this gene is a member of the ADAM (a disintegrin and metalloproteinase) protein family. ADAM family members are type I transmembrane glycoproteins known to be involved in cell adhesion and proteolytic ectodomain processing of cytokines and adhesion molecules. This protein contains multiple functional domains including a zinc-binding metalloprotease domain, a disintegrin-like domain, as well as a EGF-like domain. Through its disintegrin-like domain, this protein specifically interacts with the integrin beta chain, beta 3. It also interacts with Src family protein-tyrosine kinases in a phosphorylation-dependent manner, suggesting that this protein may function in cell-cell adhesion as well as in cellular signaling. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed.
Alias Symbols: MDC15
Protein Interaction Partner: BANP, NUP62, RBPMS, UBC, SP4, FHL3, FBXO6, SH3PXD2A, SRC, PTK6, MAPK3, MAPK1, NCK1, GRB2, SNX30, SH3RF3, SNX9, SH3GLB1, PACSIN3, ARHGEF6, ARHGEF7, SORBS2, YES1, NPHP1, LYN, LCK, HCK, FYN, SH3D19, SH3RF1, SORBS3, SNX33, SORBS1, TRIP13, SH3GL2, ABL1, MAD2L1
Protein Size: 862 - 分子量
- 70 kDa
- 基因ID
- 8751
- NCBI登录号
- NM_207196, NP_997079
- UniProt
- Q71S69
-