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HRK 抗体 (N-Term)

HRK 适用: 人, 小鼠, 大鼠, 兔, Cow, 犬 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2782598
发货至: 中国
  • 抗原 See all HRK 抗体
    HRK (Harakiri, BCL2 Interacting Protein (Contains Only BH3 Domain) (HRK))
    抗原表位
    • 15
    • 12
    • 7
    • 1
    • 1
    • 1
    N-Term
    适用
    • 25
    • 19
    • 16
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠, 兔, Cow, 犬
    宿主
    • 40
    克隆类型
    • 40
    多克隆
    标记
    • 9
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This HRK antibody is un-conjugated
    应用范围
    • 17
    • 14
    • 13
    • 13
    • 5
    • 4
    • 3
    • 1
    • 1
    Western Blotting (WB)
    序列
    MCPCPLHRGR GPPAVCACSA GRLGLRSSAA QLTAARLKAL GDELHQRTMW
    预测反应
    Cow: 100%, Dog: 100%, Human: 100%, Mouse: 83%, Rabbit: 100%, Rat: 83%
    产品特性
    This is a rabbit polyclonal antibody against HRK. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the N terminal region of human HRK
    Top Product
    Discover our top product HRK Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 91 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Lucas, Milani, Butterworth, Carmell, Scott, Clark, Cohen, Varadarajan: "High CIP2A levels correlate with an antiapoptotic phenotype that can be overcome by targeting BCL-XL in chronic myeloid leukemia." in: Leukemia, Vol. 30, Issue 6, pp. 1273-81, (2016) (PubMed).

  • 抗原
    HRK (Harakiri, BCL2 Interacting Protein (Contains Only BH3 Domain) (HRK))
    别名
    HRK (HRK 产品)
    别名
    DP5 antibody, HARAKIRI antibody, AI838259 antibody, Bid3 antibody, harakiri antibody, Dp5 antibody, harakiri, BCL2 interacting protein antibody, harakiri, BCL2 interacting protein (contains only BH3 domain) antibody, HRK antibody, Hrk antibody
    背景
    Activator of apoptosis Hrk regulates apoptosis through interaction with death-repressor proteins Bcl-2 and Bcl-X(L). The HRK protein lacks significant homology to other BCL2 family members except for an 8-amino acid region that was similar to the BCL2 hom
    Alias Symbols: DP5, HARAKIRI
    Protein Interaction Partner: BCL2L1, ELAVL1, BAD, BCL2L2, C1QBP, BCL2A1, BCL2, MCL1, BNC1,
    Protein Size: 91
    分子量
    10 kDa
    基因ID
    8739
    NCBI登录号
    NM_003806, NP_003797
    UniProt
    O00198
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