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HRK 抗体 (N-Term)

HRK 适用: 人, 小鼠, 大鼠, 兔, Cow, 犬 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2782598
发货至: 中国
  • 抗原 See all HRK 抗体
    HRK (Harakiri, BCL2 Interacting Protein (Contains Only BH3 Domain) (HRK))
    抗原表位
    • 15
    • 8
    • 3
    • 1
    • 1
    • 1
    N-Term
    适用
    • 21
    • 19
    • 16
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠, 兔, Cow, 犬
    宿主
    • 36
    克隆类型
    • 36
    多克隆
    标记
    • 9
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This HRK antibody is un-conjugated
    应用范围
    • 13
    • 13
    • 13
    • 10
    • 5
    • 4
    • 3
    • 1
    • 1
    Western Blotting (WB)
    序列
    MCPCPLHRGR GPPAVCACSA GRLGLRSSAA QLTAARLKAL GDELHQRTMW
    预测反应
    Cow: 100%, Dog: 100%, Human: 100%, Mouse: 83%, Rabbit: 100%, Rat: 83%
    产品特性
    This is a rabbit polyclonal antibody against HRK. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the N terminal region of human HRK
    Top Product
    Discover our top product HRK Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 91 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Lucas, Milani, Butterworth, Carmell, Scott, Clark, Cohen, Varadarajan: "High CIP2A levels correlate with an antiapoptotic phenotype that can be overcome by targeting BCL-XL in chronic myeloid leukemia." in: Leukemia, Vol. 30, Issue 6, pp. 1273-81, (2016) (PubMed).

  • 抗原
    HRK (Harakiri, BCL2 Interacting Protein (Contains Only BH3 Domain) (HRK))
    别名
    HRK (HRK 产品)
    背景
    Activator of apoptosis Hrk regulates apoptosis through interaction with death-repressor proteins Bcl-2 and Bcl-X(L). The HRK protein lacks significant homology to other BCL2 family members except for an 8-amino acid region that was similar to the BCL2 hom
    Alias Symbols: DP5, HARAKIRI
    Protein Interaction Partner: BCL2L1, ELAVL1, BAD, BCL2L2, C1QBP, BCL2A1, BCL2, MCL1, BNC1,
    Protein Size: 91
    分子量
    10 kDa
    基因ID
    8739
    NCBI登录号
    NM_003806, NP_003797
    UniProt
    O00198
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