CAD 抗体 (N-Term)
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- 抗原 See all CAD 抗体
- CAD (Carbamoyl-Phosphate Synthetase 2, Aspartate Transcarbamylase, and Dihydroorotase (CAD))
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠, 犬, 兔, 马, 豚鼠, Cow, 斑马鱼, 绵羊
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CAD antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- AALVLEDGSV LRGQPFGAAV STAGEVVFQT GMVGYPEALT DPSYKAQILV
- 预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Sheep: 86%, Zebrafish: 93%
- 产品特性
- This is a rabbit polyclonal antibody against CAD. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human CAD
- Top Product
- Discover our top product CAD Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 2225 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- CAD (Carbamoyl-Phosphate Synthetase 2, Aspartate Transcarbamylase, and Dihydroorotase (CAD))
- 别名
- CAD (CAD 产品)
- 别名
- Cpad antibody, AU018859 antibody, 2410008J01Rik antibody, cb456 antibody, wu:fc30c12 antibody, wu:fc33d01 antibody, wu:fc67g02 antibody, si:dkey-221h15.3 antibody, CAD antibody, xcad antibody, carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase antibody, CAD antibody, Cad antibody, cad antibody
- 背景
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CAD is a trifunctional protein which is associated with the enzymatic activities of the first 3 enzymes in the 6-step pathway of pyrimidine biosynthesis: carbamoylphosphate synthetase (CPS II), aspartate transcarbamoylase, and dihydroorotase. This protein is regulated by the mitogen-activated protein kinase (MAPK) cascade, which indicates a direct link between activation of the MAPK cascade and de novo biosynthesis of pyrimidine nucleotides.The de novo synthesis of pyrimidine nucleotides is required for mammalian cells to proliferate. This gene encodes a trifunctional protein which is associated with the enzymatic activities of the first 3 enzymes in the 6-step pathway of pyrimidine biosynthesis: carbamoylphosphate synthetase (CPS II), aspartate transcarbamoylase, and dihydroorotase. This protein is regulated by the mitogen-activated protein kinase (MAPK) cascade, which indicates a direct link between activation of the MAPK cascade and de novo biosynthesis of pyrimidine nucleotides. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: -
Protein Interaction Partner: UBC, TUBG1, TP53, SUMO2, SPRTN, STAU1, LGR4, SUMO1, NEDD8, WWOX, NEDD4, FBXO6, HDAC6, ILK, CDK2, HDAC11, HTRA2, TP63, NOS2, ITGA4, RUVBL1, XPO1, VARS, TUBB2A, TUBA4A, SMARCC2, SMARCA4, RPS3, PSMD1, PSMC2, RUVBL2, TUBB4B, SHC1, SMAD2, GRB2, CBL, CUL3, FBXO
Protein Size: 2225 - 分子量
- 243 kDa
- 基因ID
- 790
- NCBI登录号
- NM_004341, NP_004332
- UniProt
- P27708
- 途径
- Production of Molecular Mediator of Immune Response, Ribonucleoside Biosynthetic Process
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