MMP7 抗体 (C-Term)
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- 抗原 See all MMP7 抗体
- MMP7 (Matrix Metallopeptidase 7 (Matrilysin, Uterine) (MMP7))
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抗原表位
- C-Term
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适用
- 人, Cow, 马, 兔, 豚鼠, 绵羊
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This MMP7 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- AATHELGHSL GMGHSSDPNA VMYPTYGNGD PQNFKLSQDD IKGIQKLYGK
- 预测反应
- Cow: 83%, Guinea Pig: 75%, Horse: 79%, Human: 100%, Rabbit: 83%, Sheep: 100%
- 产品特性
- This is a rabbit polyclonal antibody against MMP7. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Protein A purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human MMP7
- Top Product
- Discover our top product MMP7 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 267 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- MMP7 (Matrix Metallopeptidase 7 (Matrilysin, Uterine) (MMP7))
- 别名
- MMP7 (MMP7 产品)
- 背景
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Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. MMP7 degrades proteoglycans, fibronectin, elastin and casein and differs from most MMP family members in that it lacks a conserved C-terminal protein domain. The enzyme is involved in wound healing, and studies in mice suggest that it regulates the activity of defensins in intestinal mucosa.Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades proteoglycans, fibronectin, elastin and casein and differs from most MMP family members in that it lacks a conserved C-terminal protein domain. The enzyme is involved in wound healing, and studies in mice suggest that it regulates the activity of defensins in intestinal mucosa. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3.
Alias Symbols: MMP-7, MPSL1, PUMP-1
Protein Interaction Partner: NGF, TNFSF11, CD151, BCAN, SERPINA1, PLG, SPP1, MBP, TFPI, FASLG, HBEGF, DCN, MMP9, MMP1, HAPLN1, CD44, ZBTB33,
Protein Size: 267 - 分子量
- 19 kDa
- 基因ID
- 4316
- NCBI登录号
- NM_002423, NP_002414
- UniProt
- P09237
- 途径
- Production of Molecular Mediator of Immune Response
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