CENPA 抗体 (N-Term)
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- 抗原 See all CENPA 抗体
- CENPA (Centromere Protein A (CENPA))
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抗原表位
- N-Term
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适用
- 人, 大鼠, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CENPA antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 序列
- MGPRRRSRKP EAPRRRSPSP TPTPGPSRRG PSLGASSHQH SRRRQGWLKE
- 预测反应
- Human: 100%, Mouse: 90%, Rat: 90%
- 产品特性
- This is a rabbit polyclonal antibody against CENPA. It was validated on Western Blot and immunohistochemistry.
- 纯化方法
- Protein A purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human CENPA
- Top Product
- Discover our top product CENPA Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 140 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- CENPA (Centromere Protein A (CENPA))
- 别名
- CENPA (CENPA 产品)
- 别名
- CENP-A antibody, CenH3 antibody, Cenp-A antibody, cenpx antibody, cenp-a antibody, sim2 antibody, Cenp-a antibody, RGD1563607 antibody, CENPA antibody, centromere protein A antibody, centromere protein-A antibody, centromeric histone-3 like protein antibody, centromere-specific histone H3 CENP-A antibody, cenp-A antibody, centromere protein A L homeolog antibody, histone H3-like centromeric protein A antibody, CENPA antibody, Cenpa antibody, CENP-A antibody, cenpa antibody, cenp-A antibody, cnp1 antibody, HAN_3g422 antibody, Cenp-a antibody, cenpa.L antibody, CMU_016480 antibody
- 背景
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Centromeres are the differentiated chromosomal domains that specify the mitotic behavior of chromosomes. CENPA is a centromere protein which contains a histone H3 related histone fold domain that is required for targeting to the centromere. CENPA is proposed to be a component of a modified nucleosome or nucleosome-like structure in which it replaces 1 or both copies of conventional histone H3 in the (H3-H4)2 tetrameric core of the nucleosome particle.Centromeres are the differentiated chromosomal domains that specify the mitotic behavior of chromosomes. CENPA encodes a centromere protein which contains a histone H3 related histone fold domain that is required for targeting to the centromere. CENPA is proposed to be a component of a modified nucleosome or nucleosome-like structure in which it replaces 1 or both copies of conventional histone H3 in the (H3-H4)2 tetrameric core of the nucleosome particle.
Alias Symbols: CenH3, CENP-A
Protein Interaction Partner: HIST1H4A, HIST1H2AB, H3F3A, HIST1H2BB, DIAPH3, DIAPH1, NPM1, HIST1H1A, H2AFZ, H2AFX, CENPC, CENPB, HIST3H2BB, HIST4H4, CENPT, CENPU, CENPM, CENPH, CENPN, HJURP, SUPT16H, H2AFY, AURKB, HIST1H3E, HIST2H2AC, SSRP1, RUVBL1, XRCC5, PRKDC, HNRNPU, EIF4A1, DDX5,
Protein Size: 140 - 分子量
- 16 kDa
- 基因ID
- 1058
- NCBI登录号
- NM_001809, NP_001800
- UniProt
- P49450
- 途径
- Chromatin Binding, Maintenance of Protein Location
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