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CBS 抗体 (N-Term)

CBS 适用: 人, 小鼠, 大鼠, 犬, 兔, Cow, 豚鼠, 马, Saccharomyces cerevisiae, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2782348
发货至: 中国
  • 抗原 See all CBS 抗体
    CBS (Cystathionine-beta-Synthase (CBS))
    抗原表位
    • 15
    • 9
    • 6
    • 6
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 54
    • 40
    • 11
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠, 犬, 兔, Cow, 豚鼠, 马, Saccharomyces cerevisiae, 斑马鱼
    宿主
    • 65
    • 9
    克隆类型
    • 59
    • 15
    多克隆
    标记
    • 39
    • 6
    • 6
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CBS antibody is un-conjugated
    应用范围
    • 56
    • 31
    • 16
    • 15
    • 14
    • 14
    • 13
    • 7
    • 6
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    序列
    RCIIVMPEKM SSEKVDVLRA LGAEIVRTPT NARFDSPESH VGVAWRLKNE
    预测反应
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 86%, Zebrafish: 93%
    产品特性
    This is a rabbit polyclonal antibody against CBS. It was validated on Western Blot and immunohistochemistry.
    纯化方法
    Protein A purified
    免疫原
    The immunogen is a synthetic peptide directed towards the N terminal region of human CBS
    Top Product
    Discover our top product CBS Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 551 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Yamane, Kanno, Nakamura, Fujino, Murayama: "Hydrogen sulfide-mediated regulation of contractility in the mouse ileum with electrical stimulation: roles of L-cysteine, cystathionine β-synthase, and K+ channels." in: European journal of pharmacology, Vol. 740, pp. 112-20, (2014) (PubMed).

    Geillinger, Rathmann, Köhrle, Fiamoncini, Daniel, Kipp: "Hepatic metabolite profiles in mice with a suboptimal selenium status." in: The Journal of nutritional biochemistry, Vol. 25, Issue 9, pp. 914-22, (2014) (PubMed).

    Porteus, Abdallah, Pollack, Kumai, Kwong, Yew, Milsom, Perry: "The role of hydrogen sulphide in the control of breathing in hypoxic zebrafish (Danio rerio)." in: The Journal of physiology, Vol. 592, Issue 14, pp. 3075-88, (2014) (PubMed).

    Dahlhoff, Worsch, Sailer, Hummel, Fiamoncini, Uebel, Obeid, Scherling, Geisel, Bader, Daniel: "Methyl-donor supplementation in obese mice prevents the progression of NAFLD, activates AMPK and decreases acyl-carnitine levels." in: Molecular metabolism, Vol. 3, Issue 5, pp. 565-80, (2014) (PubMed).

    Fernandes, Ribeiro, Martínez, Orensanz, Barahona, Martínez-Sáenz, Recio, Benedito, Bustamante, Carballido, García-Sacristán, Prieto, Hernández: "Endogenous hydrogen sulfide has a powerful role in inhibitory neurotransmission to the pig bladder neck." in: The Journal of urology, Vol. 189, Issue 4, pp. 1567-73, (2013) (PubMed).

    Markand, Tawfik, Ha, Gnana-Prakasam, Sonne, Ganapathy, Sen, Xian, Smith: "Cystathionine beta synthase expression in mouse retina." in: Current eye research, Vol. 38, Issue 5, pp. 597-604, (2013) (PubMed).

    Dahlhoff, Desmarchelier, Sailer, Fürst, Haag, Ulbrich, Hummel, Obeid, Geisel, Bader, Daniel: "Hepatic methionine homeostasis is conserved in C57BL/6N mice on high-fat diet despite major changes in hepatic one-carbon metabolism." in: PLoS ONE, Vol. 8, Issue 3, pp. e57387, (2013) (PubMed).

    Spellman, Ahmed, Dubach, Gardiner: "Expression of trisomic proteins in Down syndrome model systems." in: Gene, Vol. 512, Issue 2, pp. 219-25, (2012) (PubMed).

  • 抗原
    CBS (Cystathionine-beta-Synthase (CBS))
    别名
    CBS (CBS 产品)
    别名
    hip4 antibody, GB12529 antibody, CBS antibody, DDBDRAFT_0189727 antibody, DDBDRAFT_0191292 antibody, DDB_0189727 antibody, DDB_0191292 antibody, cbs antibody, AI047524 antibody, AI303044 antibody, HIP4 antibody, cb442 antibody, wu:fb37g05 antibody, wu:fm61c07 antibody, wu:fq06c06 antibody, zgc:113704 antibody, cystathionine-beta-synthase L homeolog antibody, cystathionine-beta-synthase antibody, cystathionine beta-synthase antibody, cystathionine beta-synthase CBS antibody, cystathionine beta synthase antibody, cystathionine-beta-synthase S homeolog antibody, cystathionine-beta-synthase b antibody, cbs.L antibody, cbs antibody, Cbs antibody, CBS antibody, CNA06170 antibody, Tb11.02.5400 antibody, cysB antibody, LOC100635325 antibody, cbs.S antibody, cbsb antibody
    背景
    CBS is involved in the transsulfuration pathway. The first step of this pathway, from homocysteine to cystathionine, is catalyzed by this protein. CBS deficiency can cause homocystinuria which affects many organs and tissues, including the eyes and the skeletal, vascular and central nervous systems.The protein encoded by this gene is involved in the transsulfuration pathway. The first step of this pathway, from homocysteine to cystathionine, is catalyzed by this protein. CBS deficiency can cause homocystinuria which affects many organs and tissues, including the eyes and the skeletal, vascular and central nervous systems.
    Alias Symbols: HIP4
    Protein Interaction Partner: UBASH3A, UBE2I, PSMA1, PRKAG1, PIN1, EHHADH, CBS, SUMO1, UBC, NEDD8, PIAS3, RANBP9, PIAS1, CBX4, SRP14, RAD23B, PKM, NUCB1, IREB2, HSF1, LRSAM1, C14orf142, UBA5, IPO4, GOPC, PARP6, NPLOC4, DERA, ERO1L, DBNL, GPN1, PDLIM5, PLIN3, UBA2, GPSM1, COL4A3BP, UGP
    Protein Size: 551
    分子量
    60 kDa
    基因ID
    875
    NCBI登录号
    NM_000071, NP_000062
    UniProt
    P35520
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