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SBDS 抗体 (N-Term)

SBDS 适用: 人, 小鼠, 大鼠, 犬, 斑马鱼, 马, Cow, 豚鼠, 兔 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2782336
发货至: 中国
  • 抗原 See all SBDS 抗体
    SBDS (Shwachman-Bodian-Diamond Syndrome (SBDS))
    抗原表位
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    N-Term
    适用
    • 33
    • 14
    • 14
    • 6
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    人, 小鼠, 大鼠, 犬, 斑马鱼, 马, Cow, 豚鼠, 兔
    宿主
    • 31
    • 2
    克隆类型
    • 30
    • 3
    多克隆
    标记
    • 16
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    This SBDS antibody is un-conjugated
    应用范围
    • 15
    • 10
    • 7
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    序列
    LQTHSVFVNV SKGQVAKKED LISAFGTDDQ TEICKQILTK GEVQVSDKER
    预测反应
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 85%
    产品特性
    This is a rabbit polyclonal antibody against SBDS. It was validated on Western Blot and immunohistochemistry.
    纯化方法
    Protein A purified
    免疫原
    The immunogen is a synthetic peptide directed towards the N terminal region of human SBDS
    Top Product
    Discover our top product SBDS Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 250 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Sezgin, Henson, Nihrane, Singh, Wattenberg, Alard, Ellis, Liu: "Impaired growth, hematopoietic colony formation, and ribosome maturation in human cells depleted of Shwachman-Diamond syndrome protein SBDS." in: Pediatric blood & cancer, Vol. 60, Issue 2, pp. 281-6, (2012) (PubMed).

  • 抗原
    SBDS (Shwachman-Bodian-Diamond Syndrome (SBDS))
    别名
    SBDS (SBDS 产品)
    别名
    cgi-97 antibody, sds antibody, swds antibody, zgc:56700 antibody, SDS antibody, SWDS antibody, 4733401P19Rik antibody, AI836084 antibody, CGI-97 antibody, SBDS ribosome assembly guanine nucleotide exchange factor antibody, hypothetical protein antibody, SBDS, ribosome maturation factor antibody, SBDS ribosome assembly guanine nucleotide exchange factor S homeolog antibody, SBDS ribosome maturation factor antibody, sbds antibody, LOAG_04440 antibody, sbds.S antibody, SBDS antibody, Sbds antibody
    背景
    SBDS is a member of a highly conserved protein family that exists from archaea to vertebrates and plants. The protein may function in RNA metabolism. Mutations within its gene are associated with Shwachman-Bodian-Diamond syndrome.This gene encodes a member of a highly conserved protein family that exists from archaea to vertebrates and plants. The encoded protein may function in RNA metabolism. Mutations within this gene are associated with Shwachman-Bodian-Diamond syndrome. An alternative transcript has been described, but its biological nature has not been determined. This gene has a closely linked pseudogene that is distally located.
    Alias Symbols: CGI-97, FLJ10917, SDS, SWDS
    Protein Interaction Partner: SUMO2, TYMS, PNP, IDH1, GOT1, UBC, CHAMP1, MPLKIP, MRPL53, SARNP, SLIRP, SRPRB, ACOT13, SRRM2, TIMM44, TOMM40, UBE4B, SCO2, SNX3, STX7, SF1, VDAC3, TIAL1, SPR, RBMS1, NDUFA7, NDUFA2, IDH3G, STOM, ACAA1, ACD, TERF2IP, POT1, TERF1, CLN3,
    Protein Size: 250
    分子量
    28 kDa
    基因ID
    51119
    NCBI登录号
    NM_016038, NP_057122
    UniProt
    Q9Y3A5
    途径
    Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly
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