BAAT 抗体 (N-Term)
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- 抗原 See all BAAT 抗体
- BAAT (Bile Acid CoA: Amino Acid N-Acyltransferase (Glycine N-Choloyltransferase) (BAAT))
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抗原表位
- N-Term
- 适用
- 人, 小鼠, 大鼠, 马, 兔, Cow, 犬, 豚鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This BAAT antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- IQLTATPVSA LVDEPVHIRA TGLIPFQMVS FQASLEDENG DMFYSQAHYR
- 预测反应
- Cow: 86%, Dog: 93%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 93%
- 产品特性
- This is a rabbit polyclonal antibody against BAAT. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human BAAT
- Top Product
- Discover our top product BAAT Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 418 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Repression of hepatobiliary transporters and differential regulation of classic and alternative bile acid pathways in mice during pregnancy." in: Toxicological sciences : an official journal of the Society of Toxicology, Vol. 130, Issue 2, pp. 257-68, (2012) (PubMed).
: "Genetic polymorphism of bile acid CoA: amino acid N-acyltransferase in Japanese individuals." in: Drug metabolism and pharmacokinetics, Vol. 22, Issue 2, pp. 125-8, (2007) (PubMed).
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Repression of hepatobiliary transporters and differential regulation of classic and alternative bile acid pathways in mice during pregnancy." in: Toxicological sciences : an official journal of the Society of Toxicology, Vol. 130, Issue 2, pp. 257-68, (2012) (PubMed).
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- 抗原
- BAAT (Bile Acid CoA: Amino Acid N-Acyltransferase (Glycine N-Choloyltransferase) (BAAT))
- 别名
- BAAT (BAAT 产品)
- 别名
- BACAT antibody, BAT antibody, AI118337 antibody, AI158864 antibody, kan-1 antibody, BAAT antibody, bile acid-CoA:amino acid N-acyltransferase antibody, Bile acid-CoA:amino acid N-acyltransferase antibody, bile acid-Coenzyme A: amino acid N-acyltransferase antibody, bile acid CoA:amino acid N-acyltransferase antibody, BAAT antibody, RPIC_RS10270 antibody, Bcav_2277 antibody, Rpic12D_1765 antibody, Baat antibody, LOC481635 antibody, LOC100054567 antibody, LOC786798 antibody
- 背景
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BAAT is a liver enzyme that catalyzes the transfer of C24 bile acids from the acyl-CoA thioester to either glycine or taurine, the second step in the formation of bile acid-amino acid conjugates. The bile acid conjugates then act as a detergent in the gastrointestinal tract, which enhances lipid and fat-soluble vitamin absorption. Defects in this gene are a cause of familial hypercholanemia (FHCA). The protein encoded by this gene is a liver enzyme that catalyzes the transfer of C24 bile acids from the acyl-CoA thioester to either glycine or taurine, the second step in the formation of bile acid-amino acid conjugates. The bile acid conjugates then act as a detergent in the gastrointestinal tract, which enhances lipid and fat-soluble vitamin absorption. Defects in this gene are a cause of familial hypercholanemia (FHCA). Two transcript variants encoding the same protein have been found for this gene.
Alias Symbols: BACAT, BAT, FLJ20300, MGC104432
Protein Interaction Partner: GOLGA8F, GOLGA8EP, GOLGA8DP, PEX5, SLC7A11,
Protein Size: 418 - 分子量
- 46 kDa
- 基因ID
- 570
- NCBI登录号
- NM_001701, NP_001692
- UniProt
- Q14032
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